TY  - JOUR
SP  - 85
EP  - 97
SN  - 1873-6246
A1  - Scharnowski, F
A1  - Veit, R
A1  - Zopf, R
A1  - Studer, P
A1  - Bock, S
A1  - Diedrichsen, J
A1  - Goebel, R
A1  - Mathiak, K
A1  - Birbaumer, N
A1  - Weiskopf, N
N2  - Task performance depends on ongoing brain activity which can be influenced by attention, arousal, or motivation. However, such modulating factors of cognitive efficiency are unspecific, can be difficult to control, and are not suitable to facilitate neural processing in a regionally specific manner. Here, we non-pharmacologically manipulated regionally specific brain activity using technically sophisticated real-time fMRI neurofeedback. This was accomplished by training participants to simultaneously control ongoing brain activity in circumscribed motor and memory-related brain areas, namely the supplementary motor area and the parahippocampal cortex. We found that learned voluntary control over these functionally distinct brain areas caused functionally specific behavioral effects, i.e. shortening of motor reaction times and specific interference with memory encoding. The neurofeedback approach goes beyond improving cognitive efficiency by unspecific psychological factors such as attention, arousal, or motivation. It allows for directly manipulating sustained activity of task-relevant brain regions in order to yield specific behavioral or cognitive effects.
KW  - Brain imaging
KW  -  Brain training
KW  -  Functional magnetic resonance imaging (fMRI)
KW  -  Memory
KW  -  Motor performance
KW  -  Neurofeedback
KW  -  Real-time fMRI
KW  -  Self-regulation
AV  - public
TI  - Manipulating motor performance and memory through real-time fMRI neurofeedback
N1  - © 2015 The Authors. Published by Elsevier B.V. This is an open access article under the CC BY license(http://creativecommons.org/licenses/by/4.0/).
ID  - discovery1466816
Y1  - 2015/05//
UR  - http://dx.doi.org/10.1016/j.biopsycho.2015.03.009
JF  - Biological Psychology
VL  - 108
ER  -