eprintid: 1457234
rev_number: 63
eprint_status: archive
userid: 608
dir: disk0/01/45/72/34
datestamp: 2015-01-07 15:43:28
lastmod: 2021-09-19 22:31:56
status_changed: 2015-01-07 15:43:28
type: article
metadata_visibility: show
item_issues_count: 0
creators_name: Swirski, M
creators_name: Miners, JS
creators_name: de Silva, R
creators_name: Lashley, T
creators_name: Ling, H
creators_name: Holton, J
creators_name: Revesz, T
creators_name: Love, S
title: Evaluating the relationship between amyloid-β and α-synuclein phosphorylated at Ser129 in dementia with Lewy bodies and Parkinson's disease
ispublished: pub
divisions: UCL
divisions: B02
divisions: C07
divisions: D07
divisions: F84
divisions: F86
note: © 2014 Swirski et al.; licensee BioMed Central Ltd. 
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

PMCID: PMC4248436
abstract: Lewy body and Alzheimer-type pathologies often co-exist. Several studies suggest a synergistic relationship between amyloid-β (Aβ) and α-synuclein (α-syn) accumulation. We have explored the relationship between Aβ accumulation and the phosphorylation of α-syn at serine-129 (pSer129 α-syn), in post-mortem human brain tissue and in SH-SY5Y neuroblastoma cells transfected to overexpress human α-syn.
date: 2014
official_url: http://dx.doi.org/10.1186/s13195-014-0077-y
vfaculties: VFBRS
vfaculties: VFBRS
oa_status: green
full_text_type: pub
language: eng
primo: open
primo_central: open_green
article_type_text: JOURNAL ARTICLE
verified: verified_manual
elements_source: PubMed
elements_id: 996292
doi: 10.1186/s13195-014-0077-y
pii: 77
lyricists_name: de Silva, Rohan
lyricists_name: Holton, Janice
lyricists_name: Lashley, Tammaryn
lyricists_name: Ling, Helen
lyricists_name: Revesz, Tamas
lyricists_id: RDESI16
lyricists_id: JHOLT26
lyricists_id: TJOHN05
lyricists_id: HLING02
lyricists_id: TREVE26
full_text_status: public
publication: Alzheimer's Research & Therapy
volume: 6
number: 5-8
article_number: 77
issn: 1758-9193
citation:        Swirski, M;    Miners, JS;    de Silva, R;    Lashley, T;    Ling, H;    Holton, J;    Revesz, T;           Swirski, M;  Miners, JS;  de Silva, R;  Lashley, T;  Ling, H;  Holton, J;  Revesz, T;  Love, S;   - view fewer <#>    (2014)    Evaluating the relationship between amyloid-β and α-synuclein phosphorylated at Ser129 in dementia with Lewy bodies and Parkinson's disease.                   Alzheimer's Research & Therapy , 6  (5-8)    , Article 77.  10.1186/s13195-014-0077-y <https://doi.org/10.1186/s13195-014-0077-y>.       Green open access   
 
document_url: https://discovery.ucl.ac.uk/id/eprint/1457234/1/Swirski.pdf