TY  - JOUR
TI  - Evaluating the relationship between amyloid-? and ?-synuclein phosphorylated at Ser129 in dementia with Lewy bodies and Parkinson's disease
AV  - public
VL  - 6
Y1  - 2014///
N1  - © 2014 Swirski et al.; licensee BioMed Central Ltd. 
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

PMCID: PMC4248436
IS  - 5-8
ID  - discovery1457234
N2  - Lewy body and Alzheimer-type pathologies often co-exist. Several studies suggest a synergistic relationship between amyloid-? (A?) and ?-synuclein (?-syn) accumulation. We have explored the relationship between A? accumulation and the phosphorylation of ?-syn at serine-129 (pSer129 ?-syn), in post-mortem human brain tissue and in SH-SY5Y neuroblastoma cells transfected to overexpress human ?-syn.
SN  - 1758-9193
UR  - http://dx.doi.org/10.1186/s13195-014-0077-y
JF  - Alzheimer's Research & Therapy
A1  - Swirski, M
A1  - Miners, JS
A1  - de Silva, R
A1  - Lashley, T
A1  - Ling, H
A1  - Holton, J
A1  - Revesz, T
A1  - Love, S
ER  -