%0 Journal Article
%@ 1758-9193
%A Swirski, M
%A Miners, JS
%A de Silva, R
%A Lashley, T
%A Ling, H
%A Holton, J
%A Revesz, T
%A Love, S
%D 2014
%F discovery:1457234
%J Alzheimer's Research & Therapy
%N 5-8
%T Evaluating the relationship between amyloid-β and α-synuclein phosphorylated at Ser129 in dementia with Lewy bodies and Parkinson's disease
%U https://discovery.ucl.ac.uk/id/eprint/1457234/
%V 6
%X Lewy body and Alzheimer-type pathologies often co-exist. Several studies suggest a synergistic relationship between amyloid-β (Aβ) and α-synuclein (α-syn) accumulation. We have explored the relationship between Aβ accumulation and the phosphorylation of α-syn at serine-129 (pSer129 α-syn), in post-mortem human brain tissue and in SH-SY5Y neuroblastoma cells transfected to overexpress human α-syn.
%Z © 2014 Swirski et al.; licensee BioMed Central Ltd.   This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.    PMCID: PMC4248436