@article{discovery1457234, journal = {Alzheimer's Research \& Therapy}, title = {Evaluating the relationship between amyloid-{\ensuremath{\beta}} and {\ensuremath{\alpha}}-synuclein phosphorylated at Ser129 in dementia with Lewy bodies and Parkinson's disease}, year = {2014}, note = {{\copyright} 2014 Swirski et al.; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. PMCID: PMC4248436}, volume = {6}, number = {5-8}, issn = {1758-9193}, abstract = {Lewy body and Alzheimer-type pathologies often co-exist. Several studies suggest a synergistic relationship between amyloid-{\ensuremath{\beta}} (A{\ensuremath{\beta}}) and {\ensuremath{\alpha}}-synuclein ({\ensuremath{\alpha}}-syn) accumulation. We have explored the relationship between A{\ensuremath{\beta}} accumulation and the phosphorylation of {\ensuremath{\alpha}}-syn at serine-129 (pSer129 {\ensuremath{\alpha}}-syn), in post-mortem human brain tissue and in SH-SY5Y neuroblastoma cells transfected to overexpress human {\ensuremath{\alpha}}-syn.}, author = {Swirski, M and Miners, JS and de Silva, R and Lashley, T and Ling, H and Holton, J and Revesz, T and Love, S}, url = {http://dx.doi.org/10.1186/s13195-014-0077-y} }