eprintid: 1457123
rev_number: 59
eprint_status: archive
userid: 608
dir: disk0/01/45/71/23
datestamp: 2015-03-18 11:33:08
lastmod: 2021-09-19 23:32:28
status_changed: 2017-03-23 10:21:45
type: article
metadata_visibility: show
item_issues_count: 0
creators_name: Hollingsworth, TD
creators_name: Pulliam, JRC
creators_name: Funk, S
creators_name: Truscott, JE
creators_name: Isham, V
creators_name: Lloyd, AL
title: Seven challenges for modelling indirect transmission: Vector-borne diseases, macroparasites and neglected tropical diseases
ispublished: pub
divisions: UCL
divisions: B04
divisions: C06
divisions: F61
keywords: Vector-borne disease; Macroparasites; Neglected tropical diseases; Helminths; Vectors
note: © 2014 The Authors. Published by Elsevier B.V. This is an open access article under the CC BY license(http://creativecommons.org/licenses/by/3.0/).
abstract: Many of the challenges which face modellers of directly transmitted pathogens also arise when modelling the epidemiology of pathogens with indirect transmission – whether through environmental stages, vectors, intermediate hosts or multiple hosts. In particular, understanding the roles of different hosts, how to measure contact and infection patterns, heterogeneities in contact rates, and the dynamics close to elimination are all relevant challenges, regardless of the mode of transmission. However, there remain a number of challenges that are specific and unique to modelling vector-borne diseases and macroparasites. Moreover, many of the neglected tropical diseases which are currently targeted for control and elimination are vector-borne, macroparasitic, or both, and so this article includes challenges which will assist in accelerating the control of these high-burden diseases. Here, we discuss the challenges of indirect measures of infection in humans, whether through vectors or transmission life stages and in estimating the contribution of different host groups to transmission. We also discuss the issues of “evolution-proof” interventions against vector-borne disease.
date: 2015-03
official_url: http://dx.doi.org/10.1016/j.epidem.2014.08.007
vfaculties: VMPS
oa_status: green
full_text_type: pub
language: eng
primo: open
primo_central: open_green
verified: verified_manual
elements_source: crossref
elements_id: 996176
doi: 10.1016/j.epidem.2014.08.007
lyricists_name: Isham, Valerie
lyricists_id: VSISH67
full_text_status: public
publication: Epidemics
volume: 10
pagerange: 16-20
issn: 1755-4365
citation:        Hollingsworth, TD;    Pulliam, JRC;    Funk, S;    Truscott, JE;    Isham, V;    Lloyd, AL;      (2015)    Seven challenges for modelling indirect transmission: Vector-borne diseases, macroparasites and neglected tropical diseases.                   Epidemics , 10    pp. 16-20.    10.1016/j.epidem.2014.08.007 <https://doi.org/10.1016/j.epidem.2014.08.007>.       Green open access   
 
document_url: https://discovery.ucl.ac.uk/id/eprint/1457123/3/1-s2.0-S1755436514000425-main.pdf