%X This short paper presents a preliminary description of two new protocols for privacy-preserving disease susceptibility testing, following the model proposed by Ayday et al. in [5]. We show that an alternative encoding of the patient’s SNPs can simplify private computations, and make patient-side computation on a trusted smartcard device extremely efficient. To support larger tests, we propose a second protocol variant based on secret sharing that is also simpler than the original proposal, and relies on more efficient primitives. %C Indianapolis, IN, USA %O This version is the author-accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions. %I School of Informatics and Computing, Indiana University %S PETS Workshop on Genome Privacy %L discovery1450428 %D 2014 %A George Danezis %A Emiliano De Cristofaro %E Emiliano De Cristofaro %E Steven J Murdoch %T Simpler protocols for privacy-preserving disease susceptibility testing %B Papers from the 1st PETS Workshop on Genome Privacy, held in conjunction with the 14th Privacy Enhancing Technologies Symposium