eprintid: 1447059 rev_number: 51 eprint_status: archive userid: 608 dir: disk0/01/44/70/59 datestamp: 2014-11-17 13:27:31 lastmod: 2021-10-04 01:05:53 status_changed: 2014-11-17 13:27:30 type: article metadata_visibility: show item_issues_count: 0 creators_name: Clarke, B title: Mapping the methodologies of Burkitt lymphoma ispublished: pub divisions: UCL divisions: B04 divisions: C06 divisions: F58 keywords: Burkitt lymphoma, big science, cancer viruses, geographical pathology, long safari, maps note: © 2014 The Author. Published by Elsevier Ltd. This is an open access article under the CC BY-NC-SA license (http://creativecommons.org/licenses/by-nc-sa/3.0/). abstract: While recent accounts have emphasised the planned, large-scale and systematic character of cancer virus research in the mid-C20, I argue here that a distinctive kind of small-scale scientific research existed, and made a distinctive contribution to the development of the field as a whole. Using the case of the research carried out to understand the causes of Burkitt lymphoma in Africa during the 1960s, I highlight two distinctive practices – geographical mapping and the re-purposing of existing disease infrastructure – that played a central role in this episode. My intention here is threefold: first, I will argue that this research is unlike the research practices usually identified as typical ‘big science’ research concerning cancer viruses, particularly in the United States. Second, I will argue that this kind of research is also clearly distinct from the kind of research that Derek Price (Price 1963) characterised as ‘little science’. Thirdly, I will sketch a positive characterisation of this kind of research as ‘small science’. I conclude by suggesting that this characterisation may be applied to other kinds of historical biomedical research, and that so doing may offer the pluralist a useful alternative way of understanding medical research in the twentieth century. date: 2014-12-01 publisher: Elsevier official_url: http://dx.doi.org/10.1016/j.shpsc.2014.08.005 vfaculties: VMPS oa_status: green full_text_type: pub language: eng primo: open primo_central: open_green article_type_text: Article verified: verified_manual elements_source: Manually entered elements_id: 972778 doi: 10.1016/j.shpsc.2014.08.005 lyricists_name: Clarke, Brendan lyricists_id: BOCLA19 full_text_status: public publication: Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences volume: 48 pagerange: 210-217 issn: 1369-8486 citation: Clarke, B; (2014) Mapping the methodologies of Burkitt lymphoma. Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences , 48 pp. 210-217. 10.1016/j.shpsc.2014.08.005 <https://doi.org/10.1016/j.shpsc.2014.08.005>. Green open access document_url: https://discovery.ucl.ac.uk/id/eprint/1447059/1/1-s2.0-S1369848614001216-main.pdf