eprintid: 1446921 rev_number: 42 eprint_status: archive userid: 608 dir: disk0/01/44/69/21 datestamp: 2014-09-04 13:52:15 lastmod: 2021-11-16 00:13:01 status_changed: 2014-09-04 13:52:15 type: article metadata_visibility: show item_issues_count: 0 creators_name: Ducci, A creators_name: Weheliye, WH title: Orbitally Shaken Bioreactors - Viscosity effects on flow characteristics ispublished: pub divisions: UCL divisions: B04 divisions: C05 divisions: F45 divisions: F42 keywords: Mixing, Orbitally Shaken Bioreactor, viscosity, circulation time, dissipation rate, kinetic energy, fluid mechanics abstract: Phase resolved PIV measurements were carried out to assess the flow dynamics occurring in orbitally shaken bioreactors of cylindrical geometry when working fluids of increasing viscosity are considered. Study of the phase-resolved flow characteristics allowed to built a Re-Fr map, where four quadrants associated to di fferent flow regimes are identifi ed: in-phase toroidal vortex (low Fr, high Re), out-of-phase precessional vortex (high Fr, high Re), in-phase single vortex (low Fr, low Re), out-of-phase counter-rotating toroidal vortex (high Fr, low Re). Turbulence levels are found to be significant cant only in the top right quadrant (high Fr, low Re) and scaling of the turbulent kinetic energy obtained with fluid of varying viscosity is obtained by employing the ratio of the operating Froude number to the critical Froude number associated to the mean flow transition, Fr=Frc. Estimates of the mean flow strain deformation as well as of the flow dissipative scale are provided, while a comparison is made between the flow circulation times obtained for di fferent regimes. date: 2014-11 publisher: Wiley-Blackwell official_url: http://dx.doi.org/10.1002/aic.14608 vfaculties: VENG oa_status: green full_text_type: other language: eng primo: open primo_central: open_green article_type_text: Article verified: verified_manual elements_source: Manually entered elements_id: 972704 doi: 10.1002/aic.14608 lyricists_name: Ducci, Andrea lyricists_name: Wehliye, Wehliye Hashi lyricists_id: ADUCC64 lyricists_id: WHWEH65 full_text_status: public publication: AIChE Journal volume: 60 number: 11 pagerange: 3951-3968 issn: 0001-1541 citation: Ducci, A; Weheliye, WH; (2014) Orbitally Shaken Bioreactors - Viscosity effects on flow characteristics. AIChE Journal , 60 (11) pp. 3951-3968. 10.1002/aic.14608 <https://doi.org/10.1002/aic.14608>. Green open access document_url: https://discovery.ucl.ac.uk/id/eprint/1446921/1/OSR-Flow%20properties2.pdf