TY  - JOUR
A1  - Ducci, A
A1  - Weheliye, WH
JF  - AIChE Journal
PB  - Wiley-Blackwell
SP  - 3951
VL  - 60
UR  - http://dx.doi.org/10.1002/aic.14608
ID  - discovery1446921
N2  - Phase resolved PIV measurements were carried out to assess the flow dynamics occurring in orbitally shaken bioreactors of cylindrical geometry when working fluids of increasing viscosity are considered. Study of the phase-resolved flow characteristics allowed to built a Re-Fr map, where four quadrants associated to di fferent flow regimes are identifi ed: in-phase toroidal vortex (low Fr, high Re), out-of-phase precessional vortex (high Fr, high Re), in-phase single vortex (low Fr, low Re), out-of-phase counter-rotating toroidal vortex (high Fr, low Re). Turbulence levels are found to be significant cant only in the top right quadrant (high Fr, low Re) and scaling of the turbulent kinetic energy obtained with fluid of varying viscosity is obtained by employing the ratio of the operating Froude number to the critical Froude number associated to the mean flow transition, Fr=Frc. Estimates of the mean flow strain deformation as well as of the flow dissipative scale are provided, while a comparison is made between the flow circulation times obtained for di fferent regimes.
Y1  - 2014/11//
KW  - Mixing
KW  -  Orbitally Shaken Bioreactor
KW  -  viscosity
KW  -  circulation time
KW  -  dissipation rate
KW  -  kinetic energy
KW  -  fluid mechanics
EP  - 3968
IS  - 11
AV  - public
SN  - 0001-1541
TI  - Orbitally Shaken Bioreactors - Viscosity effects on flow characteristics
ER  -