eprintid: 1436636 rev_number: 31 eprint_status: archive userid: 608 dir: disk0/01/43/66/36 datestamp: 2014-08-01 20:32:41 lastmod: 2021-09-19 23:41:02 status_changed: 2014-08-01 20:32:41 type: article metadata_visibility: show item_issues_count: 0 creators_name: Schweiger, M creators_name: Arridge, S title: The Toast plus plus software suite for forward and inverse modeling in optical tomography ispublished: pub divisions: UCL divisions: B04 divisions: C05 divisions: F48 divisions: F42 keywords: diffuse optical tomography, image reconstruction software, computer program, light transport simulation, Toast plus note: © The Authors. Published by SPIE under a Creative Commons Attribution 3.0 Unported License. Distribution or reproduction of this work in whole or in part requires full attribution of the original publication, including its DOI. abstract: We present the Toast++ open-source software environment for solving the forward and inverse problems in diffuse optical tomography (DOT). The software suite consists of a set of libraries to simulate near-infrared light propagation in highly scattering media with complex boundaries and heterogeneous internal parameter distribution, based on a finite-element solver. Steady-state, time- and frequency-domain data acquisition systems can be modeled. The forward solver is implemented in C++ and supports performance acceleration with parallelization for shared and distributed memory architectures, as well as graphics processing computation. Building on the numerical forward solver, Toast++ contains model-based iterative inverse solvers for reconstructing the volume distribution of absorption and scattering parameters from boundary measurements of light transmission. A range of regularization methods are provided, including the possibility of incorporating prior knowledge of internal structure. The user can link to the Toast++ libraries either directly to compile application programs for DOT, or make use of the included MATLAB and PYTHON bindings to generate script-based solutions. This approach allows rapid prototyping and provides a rich toolset in both environments for debugging, testing, and visualization. date: 2014-04 official_url: http://dx.doi.org/10.1117/1.JBO.19.4.040801 vfaculties: VENG oa_status: green full_text_type: pub language: eng primo: open primo_central: open_green verified: verified_manual elements_source: WoS-Lite elements_id: 966877 doi: 10.1117/1.JBO.19.4.040801 lyricists_name: Arridge, Simon lyricists_name: Schweiger, Martin Josef lyricists_id: SRARR14 lyricists_id: MSCHW35 full_text_status: public publication: Journal of Biomedical Optics volume: 19 number: 4 article_number: 040801 issn: 1083-3668 citation: Schweiger, M; Arridge, S; (2014) The Toast plus plus software suite for forward and inverse modeling in optical tomography. Journal of Biomedical Optics , 19 (4) , Article 040801. 10.1117/1.JBO.19.4.040801 <https://doi.org/10.1117/1.JBO.19.4.040801>. Green open access document_url: https://discovery.ucl.ac.uk/id/eprint/1436636/1/JBO_19_4_040801.pdf