eprintid: 1432362
rev_number: 42
eprint_status: archive
userid: 608
dir: disk0/01/43/23/62
datestamp: 2014-06-16 18:32:30
lastmod: 2021-10-21 00:08:20
status_changed: 2014-06-16 18:32:30
type: article
metadata_visibility: show
item_issues_count: 0
creators_name: Bizrah, M
creators_name: Dakin, SC
creators_name: Guo, L
creators_name: Rahman, F
creators_name: Parnell, M
creators_name: Normando, E
creators_name: Nizari, S
creators_name: Davis, B
creators_name: Younis, A
creators_name: Cordeiro, MF
title: A semi-automated technique for labeling and counting of apoptosing retinal cells
ispublished: pub
divisions: UCL
divisions: B02
divisions: C07
divisions: D08
divisions: C08
divisions: D09
divisions: G02
note: © 2014 Bizrah et al.; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, 
unless otherwise stated.
abstract: Retinal ganglion cell (RGC) loss is one of the earliest and most important cellular changes in glaucoma. The DARC (Detection of Apoptosing Retinal Cells) technology enables in vivo real-time non-invasive imaging of single apoptosing retinal cells in animal models of glaucoma and Alzheimer's disease. To date, apoptosing RGCs imaged using DARC have been counted manually. This is time-consuming, labour-intensive, vulnerable to bias, and has considerable inter- and intra-operator variability
date: 2014-06-05
official_url: http://dx.doi.org/10.1186/1471-2105-15-169
oa_status: green
full_text_type: pub
primo: open
primo_central: open_green
article_type_text: JOURNAL ARTICLE
verified: verified_manual
elements_source: PubMed
elements_id: 952265
doi: 10.1186/1471-2105-15-169
pii: 1471-2105-15-169
language_elements: ENG
lyricists_name: Cordeiro, Maria
lyricists_name: Davis, Benjamin
lyricists_name: Guo, Li
lyricists_name: Nizari, Shereen
lyricists_name: Normando, Eduardo
lyricists_id: MFCOR19
lyricists_id: BDAVI80
lyricists_id: LGUOX47
lyricists_id: SNIZA82
lyricists_id: ENORM93
full_text_status: public
publication: BMC Bioinformatics
volume: 15
number: 1
pagerange: 169 -180
citation:        Bizrah, M;    Dakin, SC;    Guo, L;    Rahman, F;    Parnell, M;    Normando, E;    Nizari, S;             ... Cordeiro, MF; + view all <#>        Bizrah, M;  Dakin, SC;  Guo, L;  Rahman, F;  Parnell, M;  Normando, E;  Nizari, S;  Davis, B;  Younis, A;  Cordeiro, MF;   - view fewer <#>    (2014)    A semi-automated technique for labeling and counting of apoptosing retinal cells.                   BMC Bioinformatics , 15  (1)   169 -180.    10.1186/1471-2105-15-169 <https://doi.org/10.1186/1471-2105-15-169>.       Green open access   
 
document_url: https://discovery.ucl.ac.uk/id/eprint/1432362/1/Semi-automated_technique.pdf