eprintid: 1427481
rev_number: 34
eprint_status: archive
userid: 608
dir: disk0/01/42/74/81
datestamp: 2014-04-23 18:55:46
lastmod: 2021-10-09 22:31:50
status_changed: 2014-04-23 18:55:46
type: article
metadata_visibility: show
item_issues_count: 0
creators_name: Dunne, L
creators_name: Hebden, J
creators_name: Tachtsidis, I
title: Development of a near infrared multi-wavelength, multi-channel, time-resolved spectrometer for measuring brain tissue haemodynamics and metabolism
ispublished: pub
divisions: UCL
divisions: B04
divisions: C05
divisions: F42
keywords: Animals, Brain, Hemodynamics, Hemoglobins, Spectroscopy, Near-Infrared, Swine
note: © Springer Science+Business Media, LLC 2014. This article is published with open access at Springerlink.com. This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author(s) and the source are credited.
abstract: We present a novel time domain functional near infrared spectroscopy system using a supercontinuum laser allowing us to measure the coefficient of absorption and scattering of up to 16 multiplexed wavelengths in the near infrared region. This is a four detector system that generates up to 3 mW of light for each wavelength with a narrow 2-3 nm FWHM bandwidth between 650 and 890 nm; each measurement of 16 wavelengths per channel can be performed up to a rate of 1 Hz. We can therefore quantify absolute haemoglobin changes in tissue and are currently investigating which and how many wavelengths are needed to resolve additional chromophores in tissue, such as water and the oxidation state of cytochrome-c-oxidase.
date: 2014
official_url: http://dx.doi.org/10.1007/978-1-4939-0620-8_24
vfaculties: VENG
oa_status: green
full_text_type: pub
language: eng
primo: open
primo_central: open_green
article_type_text: Journal Article, Research Support, Non-U.S. Gov't
verified: verified_manual
elements_source: PubMed
elements_id: 941800
doi: 10.1007/978-1-4939-0620-8_24
lyricists_name: Dunne, Luke
lyricists_name: Hebden, Jeremy
lyricists_name: Tachtsidis, Ilias
lyricists_id: DUNNE27
lyricists_id: JCHEB81
lyricists_id: ITACH19
full_text_status: public
publication: Adv Exp Med Biol
volume: 812
pagerange: 181 - 186
event_location: United States
issn: 0065-2598
citation:        Dunne, L;    Hebden, J;    Tachtsidis, I;      (2014)    Development of a near infrared multi-wavelength, multi-channel, time-resolved spectrometer for measuring brain tissue haemodynamics and metabolism.                   Adv Exp Med Biol , 812    181 - 186.    10.1007/978-1-4939-0620-8_24 <https://doi.org/10.1007/978-1-4939-0620-8_24>.       Green open access   
 
document_url: https://discovery.ucl.ac.uk/id/eprint/1427481/1/chp_10.1007_978-1-4939-0620-8_24.pdf