TY  - JOUR
N2  - We present a novel time domain functional near infrared spectroscopy system using a supercontinuum laser allowing us to measure the coefficient of absorption and scattering of up to 16 multiplexed wavelengths in the near infrared region. This is a four detector system that generates up to 3 mW of light for each wavelength with a narrow 2-3 nm FWHM bandwidth between 650 and 890 nm; each measurement of 16 wavelengths per channel can be performed up to a rate of 1 Hz. We can therefore quantify absolute haemoglobin changes in tissue and are currently investigating which and how many wavelengths are needed to resolve additional chromophores in tissue, such as water and the oxidation state of cytochrome-c-oxidase.
ID  - discovery1427481
UR  - http://dx.doi.org/10.1007/978-1-4939-0620-8_24
SN  - 0065-2598
JF  - Adv Exp Med Biol
A1  - Dunne, L
A1  - Hebden, J
A1  - Tachtsidis, I
KW  - Animals
KW  -  Brain
KW  -  Hemodynamics
KW  -  Hemoglobins
KW  -  Spectroscopy
KW  -  Near-Infrared
KW  -  Swine
TI  - Development of a near infrared multi-wavelength, multi-channel, time-resolved spectrometer for measuring brain tissue haemodynamics and metabolism
SP  - 181 
AV  - public
VL  - 812
Y1  - 2014///
EP  -  186
N1  - © Springer Science+Business Media, LLC 2014. This article is published with open access at Springerlink.com. This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author(s) and the source are credited.
ER  -