%K Aged, Aged, 80 and over, Arthritis, Rheumatoid, Cardiovascular Diseases, Chronic Disease, Cohort Studies, Comparative Effectiveness Research, Female, Great Britain, Humans, Hydroxymethylglutaryl-CoA Reductase Inhibitors, Hypercholesterolemia, Male, Middle Aged, Osteoarthritis, Outcome Assessment (Health Care), Proportional Hazards Models, Pulmonary Disease, Chronic Obstructive, Renal Insufficiency, Chronic
%A X Sheng
%A MJ Murphy
%A TM MacDonald
%A L Wei
%J BMC Public Health
%T The comparative effectiveness of statin therapy in selected chronic diseases compared with the remaining population
%C England
%D 2012
%L discovery1387173
%V 12
%P -
%O © 2012 Sheng et al.; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

PMCID: PMC3490740
%X Total cholesterol (TC) concentration is the most commonly used measure of statin efficacy in the UK. This study aimed to evaluate the effectiveness of statins in lowering TC, cardiovascular events (CV) and mortality five common chronic diseases (chronic obstructive pulmonary disease (COPD), osteoarthritis (OA), rheumatoid arthritis (RA), chronic kidney disease (CKD), and diabetes mellitus (DM)) and to compare effectiveness with the rest of the population not recorded as having these diseases.