TY - JOUR TI - The comparative effectiveness of statin therapy in selected chronic diseases compared with the remaining population VL - 12 AV - public Y1 - 2012/08/30/ N1 - © 2012 Sheng et al.; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. PMCID: PMC3490740 ID - discovery1387173 N2 - Total cholesterol (TC) concentration is the most commonly used measure of statin efficacy in the UK. This study aimed to evaluate the effectiveness of statins in lowering TC, cardiovascular events (CV) and mortality five common chronic diseases (chronic obstructive pulmonary disease (COPD), osteoarthritis (OA), rheumatoid arthritis (RA), chronic kidney disease (CKD), and diabetes mellitus (DM)) and to compare effectiveness with the rest of the population not recorded as having these diseases. SN - 1471-2458 UR - http://dx.doi.org/10.1186/1471-2458-12-712 JF - BMC Public Health KW - Aged KW - Aged KW - 80 and over KW - Arthritis KW - Rheumatoid KW - Cardiovascular Diseases KW - Chronic Disease KW - Cohort Studies KW - Comparative Effectiveness Research KW - Female KW - Great Britain KW - Humans KW - Hydroxymethylglutaryl-CoA Reductase Inhibitors KW - Hypercholesterolemia KW - Male KW - Middle Aged KW - Osteoarthritis KW - Outcome Assessment (Health Care) KW - Proportional Hazards Models KW - Pulmonary Disease KW - Chronic Obstructive KW - Renal Insufficiency KW - Chronic A1 - Sheng, X A1 - Murphy, MJ A1 - MacDonald, TM A1 - Wei, L ER -