eprintid: 1385031 rev_number: 30 eprint_status: archive userid: 608 dir: disk0/01/38/50/31 datestamp: 2013-02-09 02:57:12 lastmod: 2021-12-19 00:11:48 status_changed: 2013-02-09 02:57:12 type: article metadata_visibility: show item_issues_count: 0 creators_name: Mantz, YA creators_name: Gervasio, FL creators_name: Laino, T creators_name: Parrinello, M title: Solvent effects on charge spatial extent in DNA and implications for transfer. ispublished: pub divisions: UCL divisions: B04 divisions: C06 divisions: F56 note: © 2007 The American Physical Society abstract: To clarify the role played by water in facilitating long-range DNA charge transport, carefully designed, state-of-the-art, self-interaction corrected density-functional quantum mechanical and molecular mechanical (SIC-QM/MM) simulations are performed for the first time on two ionized adenine:thymine bridge models in explicit water solvent at finite temperature. For random solvent configurations, the charge is partially delocalized. However, a charge localization on different, well-separated adenines can be induced and is correlated with a restructuring of their first solvation shells. Thus, the importance of water in the mechanism of long-range charge transport is explicitly demonstrated, and the microscopic conditions for a charge localization are revealed. date: 2007-08-02 official_url: http://dx.doi.org/10.1103/PhysRevLett.99.058104 vfaculties: VMPS oa_status: green language: eng primo: open primo_central: open_green article_type_text: Journal Article, Research Support, U.S. Gov't, Non-P.H.S. verified: verified_manual elements_source: PubMed elements_id: 850364 doi: 10.1103/PhysRevLett.99.058104 lyricists_name: Gervasio, Francesco Luigi lyricists_id: FLGER36 full_text_status: public publication: Physical Review Letters volume: 99 number: 5 article_number: 058104 pagerange: - event_location: US issn: 0031-9007 citation: Mantz, YA; Gervasio, FL; Laino, T; Parrinello, M; (2007) Solvent effects on charge spatial extent in DNA and implications for transfer. Physical Review Letters , 99 (5) , Article 058104. 10.1103/PhysRevLett.99.058104 <https://doi.org/10.1103/PhysRevLett.99.058104>. Green open access document_url: https://discovery.ucl.ac.uk/id/eprint/1385031/1/1385031.pdf