eprintid: 1355065
rev_number: 34
eprint_status: archive
userid: 608
dir: disk0/01/35/50/65
datestamp: 2012-08-07 19:05:35
lastmod: 2021-10-04 00:12:04
status_changed: 2012-08-07 19:05:35
type: article
metadata_visibility: show
item_issues_count: 0
creators_name: Filevich, E
creators_name: Kühn, S
creators_name: Haggard, P
title: Negative motor phenomena in cortical stimulation: implications for inhibitory control of human action.
ispublished: pub
divisions: UCL
divisions: B02
divisions: C07
divisions: D05
divisions: F69
keywords: Brain Mapping, Electric Stimulation, Evoked Potentials, Motor, Humans, Motor Cortex, Movement
note: This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
abstract: Electrical stimulation of the human cortex typically elicits positive sensorimotor effects. However, many neurosurgical studies have also reported negative motor areas (NMAs) in which stimulation produces inhibition of ongoing movement. The neurocognitive implications of these studies have not been systematically explored. Here we review the neurosurgical literature on NMAs and link this to cognitive mechanisms of inhibition and their role in voluntary control of action. In particular, we discuss the functional validity of NMAs. We contest the sceptical view that negative effects following stimulation merely reflect disruption of positive motor areas. Instead, we suggest that NMAs may produce an inhibitory mechanism under ecologically valid conditions.
date: 2012-11
official_url: http://dx.doi.org/10.1016/j.cortex.2012.04.014
vfaculties: VFBRS
oa_status: green
language: eng
primo: open
primo_central: open_green
article_type_text: Journal Article, Research Support, Non-U.S. Gov't, Review
verified: verified_manual
elements_source: PubMed
elements_id: 414727
doi: 10.1016/j.cortex.2012.04.014
pii: S0010-9452(12)00141-4
language_elements: ENG
lyricists_name: Filevich, Elisa
lyricists_name: Haggard, Patrick
lyricists_id: EFILE12
lyricists_id: PHAGG98
full_text_status: public
publication: Cortex
volume: 48
number: 10
pagerange: 1251 - 1261
event_location: Italy
citation:        Filevich, E;    Kühn, S;    Haggard, P;      (2012)    Negative motor phenomena in cortical stimulation: implications for inhibitory control of human action.                   Cortex , 48  (10)   1251 - 1261.    10.1016/j.cortex.2012.04.014 <https://doi.org/10.1016/j.cortex.2012.04.014>.       Green open access   
 
document_url: https://discovery.ucl.ac.uk/id/eprint/1355065/1/1355065.pdf