TY  - JOUR
TI  - Negative motor phenomena in cortical stimulation: implications for inhibitory control of human action.
EP  -  1261
AV  - public
Y1  - 2012/11//
VL  - 48
SP  - 1251 
N1  - This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
IS  - 10
ID  - discovery1355065
N2  - Electrical stimulation of the human cortex typically elicits positive sensorimotor effects. However, many neurosurgical studies have also reported negative motor areas (NMAs) in which stimulation produces inhibition of ongoing movement. The neurocognitive implications of these studies have not been systematically explored. Here we review the neurosurgical literature on NMAs and link this to cognitive mechanisms of inhibition and their role in voluntary control of action. In particular, we discuss the functional validity of NMAs. We contest the sceptical view that negative effects following stimulation merely reflect disruption of positive motor areas. Instead, we suggest that NMAs may produce an inhibitory mechanism under ecologically valid conditions.
UR  - http://dx.doi.org/10.1016/j.cortex.2012.04.014
JF  - Cortex
KW  - Brain Mapping
KW  -  Electric Stimulation
KW  -  Evoked Potentials
KW  -  Motor
KW  -  Humans
KW  -  Motor Cortex
KW  -  Movement
A1  - Filevich, E
A1  - Kühn, S
A1  - Haggard, P
ER  -