%0 Journal Article
%A Lu, Wei-Ting
%A Kanu, Nnennaya
%D 2025
%F discovery:10206227
%I NATURE PORTFOLIO
%J Nature Cell Biology
%N 1
%P 12-13
%T FAT1 alterations contribute to chromosomal instability in cancer cells
%U https://discovery.ucl.ac.uk/id/eprint/10206227/
%V 27
%X Combining genomics data from the TRACERx non-small-cell lung cancer (NSCLC) cohort and experimental data, we report that alterations in FAT1 are selected early during lung cancer evolution and cause chromosomal instability and whole-genome doubling.
%Z This version is the author accepted manuscript. For information on re-use, please refer to the publisher's terms and conditions.