@article{discovery10206227, year = {2025}, number = {1}, month = {January}, publisher = {NATURE PORTFOLIO}, journal = {Nature Cell Biology}, pages = {12--13}, note = {This version is the author accepted manuscript. For information on re-use, please refer to the publisher's terms and conditions.}, title = {FAT1 alterations contribute to chromosomal instability in cancer cells}, volume = {27}, author = {Lu, Wei-Ting and Kanu, Nnennaya}, abstract = {Combining genomics data from the TRACERx non-small-cell lung cancer (NSCLC) cohort and experimental data, we report that alterations in FAT1 are selected early during lung cancer evolution and cause chromosomal instability and whole-genome doubling.}, url = {https://doi.org/10.1038/s41556-024-01559-9} }