eprintid: 10205885
rev_number: 10
eprint_status: archive
userid: 699
dir: disk0/10/20/58/85
datestamp: 2025-03-11 10:04:40
lastmod: 2025-03-11 10:59:56
status_changed: 2025-03-11 10:04:40
type: article
metadata_visibility: show
sword_depositor: 699
creators_name: Cowan, Frances M
creators_name: Shahmanesh, Maryam
creators_name: Revill, Paul A
creators_name: Busza, Joanna
creators_name: Sibanda, Euphemia L
creators_name: Chabata, Sungai T
creators_name: Chimbindi, Natsayi
creators_name: Choola, Tamara
creators_name: Mugurungi, Owen
creators_name: Hargreaves, James R
creators_name: Phillips, Andrew N
title: Preventing HIV in women in Africa
ispublished: inpress
divisions: UCL
divisions: B02
divisions: D01
keywords: HIV infections, Risk factors
note: This version is the author-accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
abstract: HIV incidence is declining globally, but around half of all new infections are in sub-Saharan Africa—where adolescent girls and young women bear a disproportionate burden of new infections. Those who sell sex are at particularly high risk. Despite declining incidence rates and availability of effective biomedical prevention tools, we are not on track, globally or in Africa, to achieve UNAIDS 2025 prevention targets. For those at risk, interventions that strengthen their motivation, capabilities and access to all available HIV prevention technologies are critical—for adolescent girls and women in particular, but also for epidemic control more broadly. Exciting possibilities for scaling up new and highly effective prevention technologies are close, but delivery, implementation and financing models need to be developed and urgently evaluated, in partnership with communities, or these opportunities may be lost. Here, we discuss the evolving landscape of biomedical prevention technologies for women in Africa, their implementation and financing, as well as priorities for HIV prevention research in this setting.
date: 2025-02-13
date_type: published
publisher: Nature Publishing Group
official_url: https://doi.org/10.1038/s41591-025-03535-8
full_text_type: other
language: eng
verified: verified_manual
elements_id: 2362681
doi: 10.1038/s41591-025-03535-8
medium: Print-Electronic
pii: 10.1038/s41591-025-03535-8
lyricists_name: Shahmanesh, Maryam
lyricists_name: Phillips, Andrew
lyricists_id: MSHAH03
lyricists_id: APHIL63
actors_name: Phillips, Andrew
actors_id: APHIL63
actors_role: owner
funding_acknowledgements: 214280/Z/18/Z [Wellcome Trust (Wellcome)]; 214280/Z/18/Z [Wellcome Trust (Wellcome)]; 214280/Z/18/Z [Wellcome Trust (Wellcome)]; 214280/Z/18/Z [Wellcome Trust (Wellcome)]; 214280/Z/18/Z [Wellcome Trust (Wellcome)]; 214280/Z/18/Z [Wellcome Trust (Wellcome)]; 214280/Z/18/Z [Wellcome Trust (Wellcome)]; 214280/Z/18/Z [Wellcome Trust (Wellcome)]; 214280/Z/18/Z [Wellcome Trust (Wellcome)]; 214280/Z/18/Z [Wellcome Trust (Wellcome)]; 214280/Z/18/Z [Wellcome Trust (Wellcome)]
full_text_status: restricted
publication: Nature Medicine
pages: 10
event_location: United States
issn: 1078-8956
citation:        Cowan, Frances M;    Shahmanesh, Maryam;    Revill, Paul A;    Busza, Joanna;    Sibanda, Euphemia L;    Chabata, Sungai T;    Chimbindi, Natsayi;                 ... Phillips, Andrew N; + view all <#>        Cowan, Frances M;  Shahmanesh, Maryam;  Revill, Paul A;  Busza, Joanna;  Sibanda, Euphemia L;  Chabata, Sungai T;  Chimbindi, Natsayi;  Choola, Tamara;  Mugurungi, Owen;  Hargreaves, James R;  Phillips, Andrew N;   - view fewer <#>    (2025)    Preventing HIV in women in Africa.                   Nature Medicine        10.1038/s41591-025-03535-8 <https://doi.org/10.1038/s41591-025-03535-8>.    (In press).   
 
document_url: https://discovery.ucl.ac.uk/id/eprint/10205885/1/Phillips_Cowan%20production-ready%20article%20file.pdf