eprintid: 10205725
rev_number: 7
eprint_status: archive
userid: 699
dir: disk0/10/20/57/25
datestamp: 2025-03-07 10:36:36
lastmod: 2025-03-07 10:36:36
status_changed: 2025-03-07 10:36:36
type: article
metadata_visibility: show
sword_depositor: 699
creators_name: Zhang, C
creators_name: Xu, X
creators_name: Li, B
creators_name: Li, H
creators_name: Tan, X
creators_name: Justin Jesuraj, P
creators_name: Xie, W
title: Ultra sensitive and low detection limitation non-enzymatic glucose biosensor based on heterojunction NiO@In2O3 hollow nanofibers
ispublished: pub
divisions: UCL
divisions: B04
divisions: C06
divisions: F62
divisions: ZZN
keywords: Glucose biosensor, Electrochemical detection, Saliva, Hollow nanofibers, Ultra-low detection limit
note: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
abstract: In recent years, metal oxides and their composites have been rapidly developed for non-enzymatic glucose sensors. Nevertheless, metal oxides exhibit relatively high electrical resistance, and their selectivity and signal-to-noise ratio for low-concentration glucose detection still require improvement. We here developed a NiO@In2O3 hollow nanofibers-based glucose biosensor with excellent performance. The heterojunction of NiO@In2O3 hollow nanofibers is obtained via a two-step process involving electrospinning and hydrothermal methods, respectively. The resulting sensor exhibits good activity as an electrocatalyst for the oxidation of glucose, with an ultralow limit of detection (LOD) of 2 nM and a good sensitivity of 1147 µA mM−1 cm−2, in line with excellent long-term stability, reproducibility, and good selectivity. These high-performance sensor are validated by monitoring glucose levels in human saliva. It demonstrates that heterojunction of NiO@In2O3 hollow nanofibers can be used as effective electrochemical sensing materials in practical biological applications.
date: 2025-01-01
date_type: published
publisher: ELSEVIER
official_url: https://doi.org/10.1016/j.microc.2024.112401
full_text_type: other
language: eng
verified: verified_manual
elements_id: 2344355
doi: 10.1016/j.microc.2024.112401
lyricists_name: Li, Bing
lyricists_id: BLICX39
actors_name: Li, Bing
actors_id: BLICX39
actors_role: owner
funding_acknowledgements: RS-2023-00284318 [Ministry of Science and ICT, through the National Research Foundation of Korea]; IEC\NSFC\223128 [Royal Society International Exchange Award]
full_text_status: restricted
publication: Microchemical Journal
volume: 208
article_number: 112401
pages: 8
issn: 0026-265X
citation:        Zhang, C;    Xu, X;    Li, B;    Li, H;    Tan, X;    Justin Jesuraj, P;    Xie, W;      (2025)    Ultra sensitive and low detection limitation non-enzymatic glucose biosensor based on heterojunction NiO@In2O3 hollow nanofibers.                   Microchemical Journal , 208     , Article 112401.  10.1016/j.microc.2024.112401 <https://doi.org/10.1016/j.microc.2024.112401>.      
 
document_url: https://discovery.ucl.ac.uk/id/eprint/10205725/1/MICROC-D-24-06925_R1-21-42.pdf