TY  - JOUR
TI  - Ultra sensitive and low detection limitation non-enzymatic glucose biosensor based on heterojunction NiO@In2O3 hollow nanofibers
AV  - restricted
VL  - 208
Y1  - 2025/01/01/
EP  - 8
N1  - This version is the author accepted manuscript. For information on re-use, please refer to the publisher?s terms and conditions.
N2  - In recent years, metal oxides and their composites have been rapidly developed for non-enzymatic glucose sensors. Nevertheless, metal oxides exhibit relatively high electrical resistance, and their selectivity and signal-to-noise ratio for low-concentration glucose detection still require improvement. We here developed a NiO@In2O3 hollow nanofibers-based glucose biosensor with excellent performance. The heterojunction of NiO@In2O3 hollow nanofibers is obtained via a two-step process involving electrospinning and hydrothermal methods, respectively. The resulting sensor exhibits good activity as an electrocatalyst for the oxidation of glucose, with an ultralow limit of detection (LOD) of 2 nM and a good sensitivity of 1147 渙 mM?1 cm?2, in line with excellent long-term stability, reproducibility, and good selectivity. These high-performance sensor are validated by monitoring glucose levels in human saliva. It demonstrates that heterojunction of NiO@In2O3 hollow nanofibers can be used as effective electrochemical sensing materials in practical biological applications.
ID  - discovery10205725
UR  - https://doi.org/10.1016/j.microc.2024.112401
PB  - ELSEVIER
SN  - 0026-265X
JF  - Microchemical Journal
A1  - Zhang, C
A1  - Xu, X
A1  - Li, B
A1  - Li, H
A1  - Tan, X
A1  - Justin Jesuraj, P
A1  - Xie, W
KW  - Glucose biosensor
KW  -  Electrochemical detection
KW  -  Saliva
KW  -  Hollow nanofibers
KW  -  Ultra-low detection limit
ER  -