@article{discovery10205725,
           month = {January},
          volume = {208},
            note = {This version is the author accepted manuscript. For information on re-use, please refer to the publisher's terms and conditions.},
           title = {Ultra sensitive and low detection limitation non-enzymatic glucose biosensor based on heterojunction NiO@In2O3 hollow nanofibers},
         journal = {Microchemical Journal},
            year = {2025},
       publisher = {ELSEVIER},
          author = {Zhang, C and Xu, X and Li, B and Li, H and Tan, X and Justin Jesuraj, P and Xie, W},
        keywords = {Glucose biosensor, Electrochemical detection, Saliva, Hollow nanofibers, Ultra-low detection limit},
        abstract = {In recent years, metal oxides and their composites have been rapidly developed for non-enzymatic glucose sensors. Nevertheless, metal oxides exhibit relatively high electrical resistance, and their selectivity and signal-to-noise ratio for low-concentration glucose detection still require improvement. We here developed a NiO@In2O3 hollow nanofibers-based glucose biosensor with excellent performance. The heterojunction of NiO@In2O3 hollow nanofibers is obtained via a two-step process involving electrospinning and hydrothermal methods, respectively. The resulting sensor exhibits good activity as an electrocatalyst for the oxidation of glucose, with an ultralow limit of detection (LOD) of 2 nM and a good sensitivity of 1147 uA mM?1 cm?2, in line with excellent long-term stability, reproducibility, and good selectivity. These high-performance sensor are validated by monitoring glucose levels in human saliva. It demonstrates that heterojunction of NiO@In2O3 hollow nanofibers can be used as effective electrochemical sensing materials in practical biological applications.},
            issn = {0026-265X},
             url = {https://doi.org/10.1016/j.microc.2024.112401}
}