eprintid: 10205724
rev_number: 7
eprint_status: archive
userid: 699
dir: disk0/10/20/57/24
datestamp: 2025-03-07 10:42:07
lastmod: 2025-03-07 10:42:07
status_changed: 2025-03-07 10:42:07
type: article
metadata_visibility: show
sword_depositor: 699
creators_name: Xu, Xinda
creators_name: Zhang, Chao
creators_name: Yang, Woochul
creators_name: Li, Yujia
creators_name: Li, Bing
creators_name: Haldorai, Yuvaraj
creators_name: Zhenyu, Jiang
creators_name: Xie, Wanfeng
title: Nanofiber-shaped Co3O4@In2O3 composite for high-performance enzymeless glucose sensing
ispublished: pub
divisions: UCL
divisions: B04
divisions: C06
divisions: F62
divisions: ZZN
note: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
abstract: Cobalt tetraoxide (Co3O4) holds great potential for enzymeless glucose detection due to its strong redox capabilities. However, its poor electrical conductivity limits the charge transfer and hence weakens its catalytic activity when utilized as an electrode in electrochemical sensors, such as an enzymeless glucose sensor. In this study, we developed an indium oxide (In2O3)-wrapped Co3O4 nanofibers (Co3O4@In2O3 NFs)-based electrochemical sensor for the enzymeless detection of glucose, with an ultra-low limit of detection (LoD) of 8.85 nM (S/N = 3), a wide detection range from 10 nM to 118 μM, and a high sensitivity of 1197.5 μA mM-1 cm-2. In addition, this sensor exhibits good selectivity, reproducibility, and long-term stability for over 30 days. The sensing performance of bare Co3O4 NFs towards glucose has been significantly enhanced by incorporating them within highly conductive In2O3, which is mainly attributed to the synergistic combination of the electrocatalytic activity of Co3O4 NFs, as the delicately designed core, and the excellent conductivity of In2O3, as the shell. Thus, this novel modified Co3O4@In2O3 NFs electrochemical composite has huge potential to be further developed for enzymeless glucose analysis in practical clinical settings.
date: 2025-02-04
date_type: published
publisher: Royal Society of Chemistry (RSC)
official_url: https://doi.org/10.1039/d4nr04274c
full_text_type: other
language: eng
verified: verified_manual
elements_id: 2364228
doi: 10.1039/d4nr04274c
medium: Print-Electronic
lyricists_name: Li, Bing
lyricists_id: BLICX39
actors_name: Li, Bing
actors_id: BLICX39
actors_role: owner
full_text_status: restricted
publication: Nanoscale
event_location: England
issn: 2040-3364
citation:        Xu, Xinda;    Zhang, Chao;    Yang, Woochul;    Li, Yujia;    Li, Bing;    Haldorai, Yuvaraj;    Zhenyu, Jiang;           Xu, Xinda;  Zhang, Chao;  Yang, Woochul;  Li, Yujia;  Li, Bing;  Haldorai, Yuvaraj;  Zhenyu, Jiang;  Xie, Wanfeng;   - view fewer <#>    (2025)    Nanofiber-shaped Co3O4@In2O3 composite for high-performance enzymeless glucose sensing.                   Nanoscale        10.1039/d4nr04274c <https://doi.org/10.1039/d4nr04274c>.      
 
document_url: https://discovery.ucl.ac.uk/id/eprint/10205724/1/NR-ART-10-2024-004274.R1_Proof_hi-6-14.pdf