TY  - JOUR
PB  - Royal Society of Chemistry (RSC)
UR  - https://doi.org/10.1039/d4nr04274c
SN  - 2040-3364
N2  - Cobalt tetraoxide (Co3O4) holds great potential for enzymeless glucose detection due to its strong redox capabilities. However, its poor electrical conductivity limits the charge transfer and hence weakens its catalytic activity when utilized as an electrode in electrochemical sensors, such as an enzymeless glucose sensor. In this study, we developed an indium oxide (In2O3)-wrapped Co3O4 nanofibers (Co3O4@In2O3 NFs)-based electrochemical sensor for the enzymeless detection of glucose, with an ultra-low limit of detection (LoD) of 8.85 nM (S/N = 3), a wide detection range from 10 nM to 118 ?M, and a high sensitivity of 1197.5 ?A mM-1 cm-2. In addition, this sensor exhibits good selectivity, reproducibility, and long-term stability for over 30 days. The sensing performance of bare Co3O4 NFs towards glucose has been significantly enhanced by incorporating them within highly conductive In2O3, which is mainly attributed to the synergistic combination of the electrocatalytic activity of Co3O4 NFs, as the delicately designed core, and the excellent conductivity of In2O3, as the shell. Thus, this novel modified Co3O4@In2O3 NFs electrochemical composite has huge potential to be further developed for enzymeless glucose analysis in practical clinical settings.
ID  - discovery10205724
A1  - Xu, Xinda
A1  - Zhang, Chao
A1  - Yang, Woochul
A1  - Li, Yujia
A1  - Li, Bing
A1  - Haldorai, Yuvaraj
A1  - Zhenyu, Jiang
A1  - Xie, Wanfeng
JF  - Nanoscale
Y1  - 2025/02/04/
AV  - restricted
TI  - Nanofiber-shaped Co3O4@In2O3 composite for high-performance enzymeless glucose sensing
N1  - This version is the author accepted manuscript. For information on re-use, please refer to the publisher?s terms and conditions.
ER  -