<> <http://www.w3.org/2000/01/rdf-schema#comment> "The repository administrator has not yet configured an RDF license."^^<http://www.w3.org/2001/XMLSchema#string> .
<> <http://xmlns.com/foaf/0.1/primaryTopic> <https://discovery.ucl.ac.uk/id/eprint/10205576> .
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<https://discovery.ucl.ac.uk/id/eprint/10205576> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://purl.org/ontology/bibo/Article> .
<https://discovery.ucl.ac.uk/id/eprint/10205576> <http://purl.org/dc/terms/title> "Lung ultrasound outperforms symptom-based screening to detect interstitial lung disease associated with rheumatoid arthritis"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/eprint/10205576> <http://purl.org/ontology/bibo/abstract> "OBJECTIVES: \r\nInterstitial lung disease associated with rheumatoid arthritis (RA-ILD) is linked to high mortality. Currently, effective screening tools are lacking. We assessed the role of symptoms and lung ultrasound (LUS) as potential screening tools.\r\n\r\n\r\nMETHODS: \r\n116 adult patients with RA presenting to the rheumatology outpatient clinic underwent high-resolution CT (HRCT) scans, pulmonary function tests, LUS (72 zones) and completed a Visual Analogue Scale (VAS) for cough and modified Medical Research Council dyspnoea scale (mMRC). Kruskal-Wallis (KW) tests evaluated the correlation between clinical–radiological HRCT score (no ILD, non-specific abnormalities, subclinical ILD or ILD) and the B-lines on LUS, diffusion capacity (DLCO%pred), forced vital capacity (FVC%pred), VAS Cough and mMRC. Sensitivity and specificity analyses were performed to assess symptom-based questionnaires and the number of B-lines to detect RA-ILD. Area under the receiver operating characteristics (AUROC) for detecting clinical ILD and subclinical ILD were calculated.\r\n\r\nRESULTS: \r\nIn 11.8% of patients, an ILD was detected on HRCT. Additionally, in 5%, a diagnosis of subclinical interstitial lung changes was made. The number of B-lines was most strongly associated with the clinical–radiological score (KW χ²=41.2, p=&lt;0.001). DLCO%pred was also significantly correlated with the clinical–radiological score (KW χ²=27.4, p=&lt;0.001), but FVC%pred, mMRC and VAS cough were not. Cough and dyspnoea only weakly predicted the ILD score in the sensitivity–specificity analyses, while B-lines showed AUROCs&gt;0.9 for predicting subclinical and clinical ILD.\r\n\r\nCONCLUSION: \r\nLUS is a promising tool for early detection of RA-ILD, outperforming symptom-based questionnaires or the presence of dyspnoea or cough."^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/eprint/10205576> <http://purl.org/dc/terms/date> "2025-01" .
<https://discovery.ucl.ac.uk/id/document/1834315> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://purl.org/ontology/bibo/Document> .
<https://discovery.ucl.ac.uk/id/eprint/10205576> <http://purl.org/ontology/bibo/volume> "11" .
<https://discovery.ucl.ac.uk/id/eprint/10205576> <http://purl.org/ontology/bibo/issue> "1" .
<https://discovery.ucl.ac.uk/id/org/ext-d7223ba9a97f887033fca24a24d100c4> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Organization> .
<https://discovery.ucl.ac.uk/id/org/ext-d7223ba9a97f887033fca24a24d100c4> <http://xmlns.com/foaf/0.1/name> "BMJ"^^<http://www.w3.org/2001/XMLSchema#string> .
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<https://discovery.ucl.ac.uk/id/publication/ext-20565933> <http://xmlns.com/foaf/0.1/name> "RMD Open"^^<http://www.w3.org/2001/XMLSchema#string> .
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<https://discovery.ucl.ac.uk/id/publication/ext-20565933> <http://www.w3.org/2002/07/owl#sameAs> <urn:issn:20565933> .
<https://discovery.ucl.ac.uk/id/publication/ext-20565933> <http://purl.org/ontology/bibo/issn> "20565933" .
<https://discovery.ucl.ac.uk/id/eprint/10205576> <http://purl.org/ontology/bibo/status> <http://purl.org/ontology/bibo/status/published> .
<https://discovery.ucl.ac.uk/id/eprint/10205576> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-e8cb7c72560b84ef4c88089a0fd32e0e> .
<https://discovery.ucl.ac.uk/id/eprint/10205576> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10205576#authors> .
<https://discovery.ucl.ac.uk/id/eprint/10205576#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_1> <https://discovery.ucl.ac.uk/id/person/ext-e8cb7c72560b84ef4c88089a0fd32e0e> .
<https://discovery.ucl.ac.uk/id/eprint/10205576> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-b8088b22dc9c43340fa0256279600cec> .
<https://discovery.ucl.ac.uk/id/eprint/10205576> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10205576#authors> .
<https://discovery.ucl.ac.uk/id/eprint/10205576#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_2> <https://discovery.ucl.ac.uk/id/person/ext-b8088b22dc9c43340fa0256279600cec> .
<https://discovery.ucl.ac.uk/id/eprint/10205576> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-0d52222feb90a0473cfcd4b137d6b8e9> .
<https://discovery.ucl.ac.uk/id/eprint/10205576> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10205576#authors> .
<https://discovery.ucl.ac.uk/id/eprint/10205576#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_3> <https://discovery.ucl.ac.uk/id/person/ext-0d52222feb90a0473cfcd4b137d6b8e9> .
<https://discovery.ucl.ac.uk/id/eprint/10205576> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-5e678573850ef97931475b4f8c360a28> .
<https://discovery.ucl.ac.uk/id/eprint/10205576> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10205576#authors> .
<https://discovery.ucl.ac.uk/id/eprint/10205576#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_4> <https://discovery.ucl.ac.uk/id/person/ext-5e678573850ef97931475b4f8c360a28> .
<https://discovery.ucl.ac.uk/id/eprint/10205576> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-f7cdaef18308ea078c737a26f91b29bc> .
<https://discovery.ucl.ac.uk/id/eprint/10205576> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10205576#authors> .
<https://discovery.ucl.ac.uk/id/eprint/10205576#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_5> <https://discovery.ucl.ac.uk/id/person/ext-f7cdaef18308ea078c737a26f91b29bc> .
<https://discovery.ucl.ac.uk/id/eprint/10205576> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-97841442014892c15964c89d94d35c98> .
<https://discovery.ucl.ac.uk/id/eprint/10205576> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10205576#authors> .
<https://discovery.ucl.ac.uk/id/eprint/10205576#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_6> <https://discovery.ucl.ac.uk/id/person/ext-97841442014892c15964c89d94d35c98> .
<https://discovery.ucl.ac.uk/id/eprint/10205576> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-3b3cedb8dcbc354c15d425717de0f712> .
<https://discovery.ucl.ac.uk/id/eprint/10205576> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10205576#authors> .
<https://discovery.ucl.ac.uk/id/eprint/10205576#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_7> <https://discovery.ucl.ac.uk/id/person/ext-3b3cedb8dcbc354c15d425717de0f712> .
<https://discovery.ucl.ac.uk/id/eprint/10205576> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-88d47914128127b8216e39fe01948fab> .
<https://discovery.ucl.ac.uk/id/eprint/10205576> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10205576#authors> .
<https://discovery.ucl.ac.uk/id/eprint/10205576#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_8> <https://discovery.ucl.ac.uk/id/person/ext-88d47914128127b8216e39fe01948fab> .
<https://discovery.ucl.ac.uk/id/eprint/10205576> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-060ddb0e7c2178a58b18e7c25c317781> .
<https://discovery.ucl.ac.uk/id/eprint/10205576> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10205576#authors> .
<https://discovery.ucl.ac.uk/id/eprint/10205576#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_9> <https://discovery.ucl.ac.uk/id/person/ext-060ddb0e7c2178a58b18e7c25c317781> .
<https://discovery.ucl.ac.uk/id/eprint/10205576> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-737d06d1b275bde07cc4e76e0f58ad13> .
<https://discovery.ucl.ac.uk/id/eprint/10205576> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10205576#authors> .
<https://discovery.ucl.ac.uk/id/eprint/10205576#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_10> <https://discovery.ucl.ac.uk/id/person/ext-737d06d1b275bde07cc4e76e0f58ad13> .
<https://discovery.ucl.ac.uk/id/eprint/10205576> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-9d465abd828bb82e482775c32600840e> .
<https://discovery.ucl.ac.uk/id/eprint/10205576> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10205576#authors> .
<https://discovery.ucl.ac.uk/id/eprint/10205576#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_11> <https://discovery.ucl.ac.uk/id/person/ext-9d465abd828bb82e482775c32600840e> .
<https://discovery.ucl.ac.uk/id/eprint/10205576> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-da7915b2ee5f7bcae93eb26925bb4bb2> .
<https://discovery.ucl.ac.uk/id/eprint/10205576> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10205576#authors> .
<https://discovery.ucl.ac.uk/id/eprint/10205576#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_12> <https://discovery.ucl.ac.uk/id/person/ext-da7915b2ee5f7bcae93eb26925bb4bb2> .
<https://discovery.ucl.ac.uk/id/eprint/10205576> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-643b3617e7ecc16754b2ab61480dc75d> .
<https://discovery.ucl.ac.uk/id/eprint/10205576> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10205576#authors> .
<https://discovery.ucl.ac.uk/id/eprint/10205576#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_13> <https://discovery.ucl.ac.uk/id/person/ext-643b3617e7ecc16754b2ab61480dc75d> .
<https://discovery.ucl.ac.uk/id/eprint/10205576> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-ca23ad29f430bbcacd0e7d87973e22c3> .
<https://discovery.ucl.ac.uk/id/eprint/10205576> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10205576#authors> .
<https://discovery.ucl.ac.uk/id/eprint/10205576#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_14> <https://discovery.ucl.ac.uk/id/person/ext-ca23ad29f430bbcacd0e7d87973e22c3> .
<https://discovery.ucl.ac.uk/id/eprint/10205576> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-75fbecaa5b25e524692ef9aaea774198> .
<https://discovery.ucl.ac.uk/id/eprint/10205576> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10205576#authors> .
<https://discovery.ucl.ac.uk/id/eprint/10205576#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_15> <https://discovery.ucl.ac.uk/id/person/ext-75fbecaa5b25e524692ef9aaea774198> .
<https://discovery.ucl.ac.uk/id/person/ext-b8088b22dc9c43340fa0256279600cec> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery.ucl.ac.uk/id/person/ext-b8088b22dc9c43340fa0256279600cec> <http://xmlns.com/foaf/0.1/givenName> "Alexandros"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-b8088b22dc9c43340fa0256279600cec> <http://xmlns.com/foaf/0.1/familyName> "Kalkanis"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-b8088b22dc9c43340fa0256279600cec> <http://xmlns.com/foaf/0.1/name> "Alexandros Kalkanis"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-97841442014892c15964c89d94d35c98> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery.ucl.ac.uk/id/person/ext-97841442014892c15964c89d94d35c98> <http://xmlns.com/foaf/0.1/givenName> "Heleen"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-97841442014892c15964c89d94d35c98> <http://xmlns.com/foaf/0.1/familyName> "Cypers"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-97841442014892c15964c89d94d35c98> <http://xmlns.com/foaf/0.1/name> "Heleen Cypers"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-737d06d1b275bde07cc4e76e0f58ad13> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery.ucl.ac.uk/id/person/ext-737d06d1b275bde07cc4e76e0f58ad13> <http://xmlns.com/foaf/0.1/givenName> "Barbara"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-737d06d1b275bde07cc4e76e0f58ad13> <http://xmlns.com/foaf/0.1/familyName> "Neerinckx"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-737d06d1b275bde07cc4e76e0f58ad13> <http://xmlns.com/foaf/0.1/name> "Barbara Neerinckx"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-f7cdaef18308ea078c737a26f91b29bc> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery.ucl.ac.uk/id/person/ext-f7cdaef18308ea078c737a26f91b29bc> <http://xmlns.com/foaf/0.1/givenName> "Emanuela Elsa"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-f7cdaef18308ea078c737a26f91b29bc> <http://xmlns.com/foaf/0.1/familyName> "Cortesi"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-f7cdaef18308ea078c737a26f91b29bc> <http://xmlns.com/foaf/0.1/name> "Emanuela Elsa Cortesi"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-643b3617e7ecc16754b2ab61480dc75d> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery.ucl.ac.uk/id/person/ext-643b3617e7ecc16754b2ab61480dc75d> <http://xmlns.com/foaf/0.1/givenName> "Laurens J"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-643b3617e7ecc16754b2ab61480dc75d> <http://xmlns.com/foaf/0.1/familyName> "De Sadeleer"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-643b3617e7ecc16754b2ab61480dc75d> <http://xmlns.com/foaf/0.1/name> "Laurens J De Sadeleer"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-e8cb7c72560b84ef4c88089a0fd32e0e> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery.ucl.ac.uk/id/person/ext-e8cb7c72560b84ef4c88089a0fd32e0e> <http://xmlns.com/foaf/0.1/givenName> "Marie"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-e8cb7c72560b84ef4c88089a0fd32e0e> <http://xmlns.com/foaf/0.1/familyName> "Vermant"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-e8cb7c72560b84ef4c88089a0fd32e0e> <http://xmlns.com/foaf/0.1/name> "Marie Vermant"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-060ddb0e7c2178a58b18e7c25c317781> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery.ucl.ac.uk/id/person/ext-060ddb0e7c2178a58b18e7c25c317781> <http://xmlns.com/foaf/0.1/givenName> "Stefan"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-060ddb0e7c2178a58b18e7c25c317781> <http://xmlns.com/foaf/0.1/familyName> "Gogaert"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-060ddb0e7c2178a58b18e7c25c317781> <http://xmlns.com/foaf/0.1/name> "Stefan Gogaert"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-0d52222feb90a0473cfcd4b137d6b8e9> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery.ucl.ac.uk/id/person/ext-0d52222feb90a0473cfcd4b137d6b8e9> <http://xmlns.com/foaf/0.1/givenName> "Joseph"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-0d52222feb90a0473cfcd4b137d6b8e9> <http://xmlns.com/foaf/0.1/familyName> "Jacob"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-0d52222feb90a0473cfcd4b137d6b8e9> <http://xmlns.com/foaf/0.1/name> "Joseph Jacob"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-ca23ad29f430bbcacd0e7d87973e22c3> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery.ucl.ac.uk/id/person/ext-ca23ad29f430bbcacd0e7d87973e22c3> <http://xmlns.com/foaf/0.1/givenName> "Patrick"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-ca23ad29f430bbcacd0e7d87973e22c3> <http://xmlns.com/foaf/0.1/familyName> "Verschueren"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-ca23ad29f430bbcacd0e7d87973e22c3> <http://xmlns.com/foaf/0.1/name> "Patrick Verschueren"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-88d47914128127b8216e39fe01948fab> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
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