eprintid: 10205564
rev_number: 24
eprint_status: archive
userid: 699
dir: disk0/10/20/55/64
datestamp: 2025-03-05 08:08:31
lastmod: 2025-03-05 08:08:31
status_changed: 2025-03-05 08:08:31
type: article
metadata_visibility: show
sword_depositor: 699
creators_name: Melegkovits, Eirini Aikaterini
creators_name: Tang, Rui
creators_name: Pounds, Olivia
creators_name: Ashcroft, Katie
creators_name: Jung, Paul
creators_name: Kennerley, Helen
creators_name: Fonagy, Peter
creators_name: Bloomfield, Michael
title: The experience and role of dissociation in psychosis following developmental trauma: A systematic review
ispublished: pub
divisions: UCL
divisions: B02
divisions: C07
divisions: D05
divisions: F66
keywords: Abuse, Dissociation, Hallucination, Trauma, Psychosis
note: Under a Creative Commons license https://creativecommons.org/licenses/by/4.0/
abstract: Developmental trauma (DT), defined as abuse or neglect before age 18, is linked with elevated risk and poorer outcomes in psychosis. This systematic review aimed to elucidate the relationship between DT and dissociation in psychosis and discern the potential mediating role of dissociation in the link between DT and psychotic manifestations. Our study protocol was pre-registered with PROSPERO (CRD42022330026). We adopted broad criteria, including a variety of methodologies exploring dissociation post-DT in individuals exhibiting psychosis or psychotic features. Risk of bias was assessed for all included studies. Our review incorporated 40 studies, totalling 6941 participants. A significant moderate association was observed between DT and dissociation (r = 0.33 (95 %CI: 0.28–0.38)), underscored by dose-response effects. Sexual and emotional abuse demonstrated the most robust associations with dissociation. Individuals with psychosis and DT reported elevated dissociation relative to their non-traumatized counterparts. Dissociation mediated the link between DT and positive psychotic symptoms, notably hallucinations, across clinical and general populations. Five studies pinpointed dissociation's mediating role in tying DT to paranoia and delusional ideation. The review delves into clinical considerations, emphasizing screening for psychotic and dissociative symptoms in DT survivors, and outlining dissociation management strategies. Future research, employing longitudinal, qualitative, and experimental approaches, remains paramount.
date: 2025-02
date_type: published
publisher: Elsevier BV
official_url: https://doi.org/10.1016/j.cpr.2025.102564
oa_status: green
full_text_type: other
language: eng
primo: open
primo_central: open_green
verified: verified_manual
elements_id: 2365747
doi: 10.1016/j.cpr.2025.102564
lyricists_name: Fonagy, Peter
lyricists_id: PFONA04
actors_name: Fonagy, Peter
actors_name: Farrar, Clare
actors_id: PFONA04
actors_id: CFARR38
actors_role: owner
actors_role: impersonator
full_text_status: public
publication: Clinical Psychology Review
article_number: 102564
issn: 0272-7358
citation:        Melegkovits, Eirini Aikaterini;    Tang, Rui;    Pounds, Olivia;    Ashcroft, Katie;    Jung, Paul;    Kennerley, Helen;    Fonagy, Peter;           Melegkovits, Eirini Aikaterini;  Tang, Rui;  Pounds, Olivia;  Ashcroft, Katie;  Jung, Paul;  Kennerley, Helen;  Fonagy, Peter;  Bloomfield, Michael;   - view fewer <#>    (2025)    The experience and role of dissociation in psychosis following developmental trauma: A systematic review.                   Clinical Psychology Review      , Article 102564.  10.1016/j.cpr.2025.102564 <https://doi.org/10.1016/j.cpr.2025.102564>.       Green open access   
 
document_url: https://discovery.ucl.ac.uk/id/eprint/10205564/13/Fonagy_1-s2.0-S0272735825000303-main.pdf