<> <http://www.w3.org/2000/01/rdf-schema#comment> "The repository administrator has not yet configured an RDF license."^^<http://www.w3.org/2001/XMLSchema#string> .
<> <http://xmlns.com/foaf/0.1/primaryTopic> <https://discovery.ucl.ac.uk/id/eprint/10203934> .
<https://discovery.ucl.ac.uk/id/eprint/10203934> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://purl.org/ontology/bibo/AcademicArticle> .
<https://discovery.ucl.ac.uk/id/eprint/10203934> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://purl.org/ontology/bibo/Article> .
<https://discovery.ucl.ac.uk/id/eprint/10203934> <http://purl.org/dc/terms/title> "Plasmonic Nanoparticles for Photothermal Therapy: Benchmarking of Photothermal Properties and Modeling of Heating at Depth in Human Tissues"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/eprint/10203934> <http://purl.org/ontology/bibo/abstract> "Many different types of nanoparticles have been developed for photothermal therapy (PTT), but directly comparing their efficacy as heaters and determining how they will perform when localized at depth in tissue remains complex. To choose the optimal nanoparticle for a desired hyperthermic therapy, it is vital to understand how efficiently different nanoparticles extinguish laser light and convert that energy to heat. In this paper, we apply photothermal mass conversion efficiency (ηm) as a metric to compare nanoparticles of different shapes, sizes, and conversion efficiencies. We selected silica-gold nanoshells (AuNShells), gold nanorods (AuNRs), and gold nanostars (AuNStars) as three archetypal nanoparticles for PTT and measured the ηm of each to demonstrate the importance of considering both photothermal efficiency and extinction cross section when comparing nanoparticles. By utilizing a Monte Carlo model, we further applied ηm to model how AuNRs performed when located at tissue depths of 0–30 mm by simulating the depth penetration of near-infrared (NIR) laser light. These results show how nanoparticle concentration, laser power, and tissue depth influence the ramp time to a hyperthermic temperature of 43 °C. The methodology outlined in this paper creates a framework to benchmark the heating efficacy of different nanoparticle types and a means of estimating the feasibility of nanoparticle-mediated PTT at depth in the NIR window. These are key considerations when predicting the potential clinical impact in the early stages of nanoparticle design."^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/eprint/10203934> <http://purl.org/dc/terms/date> "2025-01-09" .
<https://discovery.ucl.ac.uk/id/document/1821346> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://purl.org/ontology/bibo/Document> .
<https://discovery.ucl.ac.uk/id/eprint/10203934> <http://purl.org/ontology/bibo/volume> "129" .
<https://discovery.ucl.ac.uk/id/eprint/10203934> <http://purl.org/ontology/bibo/issue> "3" .
<https://discovery.ucl.ac.uk/id/org/ext-30b56b3b235669f6a72b7f9974ad6130> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Organization> .
<https://discovery.ucl.ac.uk/id/org/ext-30b56b3b235669f6a72b7f9974ad6130> <http://xmlns.com/foaf/0.1/name> "AMER CHEMICAL SOC"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/eprint/10203934> <http://purl.org/dc/terms/publisher> <https://discovery.ucl.ac.uk/id/org/ext-30b56b3b235669f6a72b7f9974ad6130> .
<https://discovery.ucl.ac.uk/id/publication/ext-19327447> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://purl.org/ontology/bibo/Collection> .
<https://discovery.ucl.ac.uk/id/publication/ext-19327447> <http://xmlns.com/foaf/0.1/name> "The Journal of Physical Chemistry C"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/eprint/10203934> <http://purl.org/dc/terms/isPartOf> <https://discovery.ucl.ac.uk/id/publication/ext-19327447> .
<https://discovery.ucl.ac.uk/id/publication/ext-19327447> <http://www.w3.org/2002/07/owl#sameAs> <urn:issn:19327447> .
<https://discovery.ucl.ac.uk/id/publication/ext-19327447> <http://purl.org/ontology/bibo/issn> "19327447" .
<https://discovery.ucl.ac.uk/id/eprint/10203934> <http://purl.org/ontology/bibo/status> <http://purl.org/ontology/bibo/status/published> .
<https://discovery.ucl.ac.uk/id/eprint/10203934> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-6509aa9734790edbb09edc9a665ab6bf> .
<https://discovery.ucl.ac.uk/id/eprint/10203934> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10203934#authors> .
<https://discovery.ucl.ac.uk/id/eprint/10203934#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_1> <https://discovery.ucl.ac.uk/id/person/ext-6509aa9734790edbb09edc9a665ab6bf> .
<https://discovery.ucl.ac.uk/id/eprint/10203934> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-a965594f3b96c4dd616f9f1ee91056dc> .
<https://discovery.ucl.ac.uk/id/eprint/10203934> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10203934#authors> .
<https://discovery.ucl.ac.uk/id/eprint/10203934#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_2> <https://discovery.ucl.ac.uk/id/person/ext-a965594f3b96c4dd616f9f1ee91056dc> .
<https://discovery.ucl.ac.uk/id/eprint/10203934> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-a386020a84534aa94bbd19f143ff872d> .
<https://discovery.ucl.ac.uk/id/eprint/10203934> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10203934#authors> .
<https://discovery.ucl.ac.uk/id/eprint/10203934#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_3> <https://discovery.ucl.ac.uk/id/person/ext-a386020a84534aa94bbd19f143ff872d> .
<https://discovery.ucl.ac.uk/id/eprint/10203934> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-1267705d57def95d3c32673a84b91fd1> .
<https://discovery.ucl.ac.uk/id/eprint/10203934> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10203934#authors> .
<https://discovery.ucl.ac.uk/id/eprint/10203934#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_4> <https://discovery.ucl.ac.uk/id/person/ext-1267705d57def95d3c32673a84b91fd1> .
<https://discovery.ucl.ac.uk/id/eprint/10203934> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-53cf5a018c68955448ee4e661fe987a5> .
<https://discovery.ucl.ac.uk/id/eprint/10203934> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10203934#authors> .
<https://discovery.ucl.ac.uk/id/eprint/10203934#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_5> <https://discovery.ucl.ac.uk/id/person/ext-53cf5a018c68955448ee4e661fe987a5> .
<https://discovery.ucl.ac.uk/id/eprint/10203934> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-6dae09ec1111b98302af18c31bcc44f6> .
<https://discovery.ucl.ac.uk/id/eprint/10203934> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10203934#authors> .
<https://discovery.ucl.ac.uk/id/eprint/10203934#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_6> <https://discovery.ucl.ac.uk/id/person/ext-6dae09ec1111b98302af18c31bcc44f6> .
<https://discovery.ucl.ac.uk/id/eprint/10203934> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-be071b05750a3d994e910f5f5ce11115> .
<https://discovery.ucl.ac.uk/id/eprint/10203934> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10203934#authors> .
<https://discovery.ucl.ac.uk/id/eprint/10203934#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_7> <https://discovery.ucl.ac.uk/id/person/ext-be071b05750a3d994e910f5f5ce11115> .
<https://discovery.ucl.ac.uk/id/eprint/10203934> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-2654512b1a061a708d3b5c534ebd2ebf> .
<https://discovery.ucl.ac.uk/id/eprint/10203934> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10203934#authors> .
<https://discovery.ucl.ac.uk/id/eprint/10203934#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_8> <https://discovery.ucl.ac.uk/id/person/ext-2654512b1a061a708d3b5c534ebd2ebf> .
<https://discovery.ucl.ac.uk/id/eprint/10203934> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-2a64d78e46024ef8e966d7e18b8481f5> .
<https://discovery.ucl.ac.uk/id/eprint/10203934> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10203934#authors> .
<https://discovery.ucl.ac.uk/id/eprint/10203934#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_9> <https://discovery.ucl.ac.uk/id/person/ext-2a64d78e46024ef8e966d7e18b8481f5> .
<https://discovery.ucl.ac.uk/id/eprint/10203934> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-ba1c6e1cfe48049fd4ee5c61137b317d> .
<https://discovery.ucl.ac.uk/id/eprint/10203934> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10203934#authors> .
<https://discovery.ucl.ac.uk/id/eprint/10203934#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_10> <https://discovery.ucl.ac.uk/id/person/ext-ba1c6e1cfe48049fd4ee5c61137b317d> .
<https://discovery.ucl.ac.uk/id/eprint/10203934> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-ca786beeb21b1a26965ddb3b532a9772> .
<https://discovery.ucl.ac.uk/id/eprint/10203934> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10203934#authors> .
<https://discovery.ucl.ac.uk/id/eprint/10203934#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_11> <https://discovery.ucl.ac.uk/id/person/ext-ca786beeb21b1a26965ddb3b532a9772> .
<https://discovery.ucl.ac.uk/id/eprint/10203934> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-341e8f3d55647e80987ee2c6dd60e0cc> .
<https://discovery.ucl.ac.uk/id/eprint/10203934> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10203934#authors> .
<https://discovery.ucl.ac.uk/id/eprint/10203934#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_12> <https://discovery.ucl.ac.uk/id/person/ext-341e8f3d55647e80987ee2c6dd60e0cc> .
<https://discovery.ucl.ac.uk/id/eprint/10203934> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-3390a5992e83b3b94a90d191030b1789> .
<https://discovery.ucl.ac.uk/id/eprint/10203934> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10203934#authors> .
<https://discovery.ucl.ac.uk/id/eprint/10203934#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_13> <https://discovery.ucl.ac.uk/id/person/ext-3390a5992e83b3b94a90d191030b1789> .
<https://discovery.ucl.ac.uk/id/person/ext-ca786beeb21b1a26965ddb3b532a9772> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery.ucl.ac.uk/id/person/ext-ca786beeb21b1a26965ddb3b532a9772> <http://xmlns.com/foaf/0.1/givenName> "Pavel"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-ca786beeb21b1a26965ddb3b532a9772> <http://xmlns.com/foaf/0.1/familyName> "Matousek"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-ca786beeb21b1a26965ddb3b532a9772> <http://xmlns.com/foaf/0.1/name> "Pavel Matousek"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-a965594f3b96c4dd616f9f1ee91056dc> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery.ucl.ac.uk/id/person/ext-a965594f3b96c4dd616f9f1ee91056dc> <http://xmlns.com/foaf/0.1/givenName> "Marzieh"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-a965594f3b96c4dd616f9f1ee91056dc> <http://xmlns.com/foaf/0.1/familyName> "Salimi"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-a965594f3b96c4dd616f9f1ee91056dc> <http://xmlns.com/foaf/0.1/name> "Marzieh Salimi"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-a386020a84534aa94bbd19f143ff872d> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery.ucl.ac.uk/id/person/ext-a386020a84534aa94bbd19f143ff872d> <http://xmlns.com/foaf/0.1/givenName> "Laura"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-a386020a84534aa94bbd19f143ff872d> <http://xmlns.com/foaf/0.1/familyName> "Moran"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-a386020a84534aa94bbd19f143ff872d> <http://xmlns.com/foaf/0.1/name> "Laura Moran"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-53cf5a018c68955448ee4e661fe987a5> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery.ucl.ac.uk/id/person/ext-53cf5a018c68955448ee4e661fe987a5> <http://xmlns.com/foaf/0.1/givenName> "Megha"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-53cf5a018c68955448ee4e661fe987a5> <http://xmlns.com/foaf/0.1/familyName> "Mehta"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-53cf5a018c68955448ee4e661fe987a5> <http://xmlns.com/foaf/0.1/name> "Megha Mehta"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-1267705d57def95d3c32673a84b91fd1> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery.ucl.ac.uk/id/person/ext-1267705d57def95d3c32673a84b91fd1> <http://xmlns.com/foaf/0.1/givenName> "Ioana"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-1267705d57def95d3c32673a84b91fd1> <http://xmlns.com/foaf/0.1/familyName> "Blein-Dezayes"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-1267705d57def95d3c32673a84b91fd1> <http://xmlns.com/foaf/0.1/name> "Ioana Blein-Dezayes"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-2654512b1a061a708d3b5c534ebd2ebf> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery.ucl.ac.uk/id/person/ext-2654512b1a061a708d3b5c534ebd2ebf> <http://xmlns.com/foaf/0.1/givenName> "Benjamin"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-2654512b1a061a708d3b5c534ebd2ebf> <http://xmlns.com/foaf/0.1/familyName> "Gardner"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-2654512b1a061a708d3b5c534ebd2ebf> <http://xmlns.com/foaf/0.1/name> "Benjamin Gardner"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-341e8f3d55647e80987ee2c6dd60e0cc> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery.ucl.ac.uk/id/person/ext-341e8f3d55647e80987ee2c6dd60e0cc> <http://xmlns.com/foaf/0.1/givenName> "Tim"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-341e8f3d55647e80987ee2c6dd60e0cc> <http://xmlns.com/foaf/0.1/familyName> "Harries"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-341e8f3d55647e80987ee2c6dd60e0cc> <http://xmlns.com/foaf/0.1/name> "Tim Harries"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-3390a5992e83b3b94a90d191030b1789> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery.ucl.ac.uk/id/person/ext-3390a5992e83b3b94a90d191030b1789> <http://xmlns.com/foaf/0.1/givenName> "Nick"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-3390a5992e83b3b94a90d191030b1789> <http://xmlns.com/foaf/0.1/familyName> "Stone"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-3390a5992e83b3b94a90d191030b1789> <http://xmlns.com/foaf/0.1/name> "Nick Stone"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-6509aa9734790edbb09edc9a665ab6bf> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery.ucl.ac.uk/id/person/ext-6509aa9734790edbb09edc9a665ab6bf> <http://xmlns.com/foaf/0.1/givenName> "William H"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-6509aa9734790edbb09edc9a665ab6bf> <http://xmlns.com/foaf/0.1/familyName> "Skinner"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-6509aa9734790edbb09edc9a665ab6bf> <http://xmlns.com/foaf/0.1/name> "William H Skinner"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-2a64d78e46024ef8e966d7e18b8481f5> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery.ucl.ac.uk/id/person/ext-2a64d78e46024ef8e966d7e18b8481f5> <http://xmlns.com/foaf/0.1/givenName> "Francesca"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-2a64d78e46024ef8e966d7e18b8481f5> <http://xmlns.com/foaf/0.1/familyName> "Palombo"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-2a64d78e46024ef8e966d7e18b8481f5> <http://xmlns.com/foaf/0.1/name> "Francesca Palombo"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-6dae09ec1111b98302af18c31bcc44f6> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery.ucl.ac.uk/id/person/ext-6dae09ec1111b98302af18c31bcc44f6> <http://xmlns.com/foaf/0.1/givenName> "Sara"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-6dae09ec1111b98302af18c31bcc44f6> <http://xmlns.com/foaf/0.1/familyName> "Mosca"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-6dae09ec1111b98302af18c31bcc44f6> <http://xmlns.com/foaf/0.1/name> "Sara Mosca"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-ba1c6e1cfe48049fd4ee5c61137b317d> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
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