eprintid: 10203603
rev_number: 11
eprint_status: archive
userid: 699
dir: disk0/10/20/36/03
datestamp: 2025-02-27 10:32:57
lastmod: 2025-02-27 10:32:57
status_changed: 2025-02-27 10:32:57
type: thesis
metadata_visibility: show
sword_depositor: 699
creators_name: Boney, Ritchie Oliver Caleb
title: Improving the quality and patient relevance of perioperative research
ispublished: unpub
divisions: UCL
divisions: B02
divisions: C10
divisions: D16
note: Copyright © The Author 2025. Original content in this thesis is licensed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0) Licence (https://creativecommons.org/licenses/by-nc/4.0/). Any third-party copyright material present remains the property of its respective owner(s) and is licensed under its existing terms. Access may initially be restricted at the author’s request.
abstract: Background: Health research has recently evolved from being exclusively expert-led towards an inclusive collaboration between patients and healthcare professionals (HCPs). However, Anaesthesia and Perioperative Medicine (APOM) have lagged other disciplines in embracing this collaborative approach. We conducted two research initiatives to demonstrate the feasibility and benefits of stakeholder participation. The first – the Anaesthesia and Perioperative Care Priority Setting Partnership (APoC-PSP) – brought stakeholders together to agree priorities for future research. The second – the Core Outcome Measures for Perioperative and Anaesthetic Care (COMPAC) initiative – employed stakeholder collaboration to develop a Core Outcome Set (COS) for future trials. Methods: APoC-PSP: Stakeholders volunteered research ideas and suggestions via an online survey. Those suggestions were condensed into a shortlist and prioritised through a second online survey. Finally, the highest priority topics were discussed at a stakeholder workshop, where the ‘Top Ten’ research priorities were agreed. COMPAC: A systematic review was conducted to understand recent trends in APOM trial outcome reporting. We then undertook a survey seeking stakeholder views regarding important outcomes after major surgery. Stakeholder representatives then participated in a modified Delphi process to agree a perioperative Core Outcome Set. Results: APoC-PSP: 1,476 research ideas and suggestions were received from 623 contributors. These were refined into 92 ‘summary’ research questions and ranked by 1,718 second survey respondents. At the final workshop, 23 stakeholder representatives discussed the 25 highest-ranked questions and agreed the ‘Top Ten’ research priorities. 4 COMPAC: The systematic review found widespread variation in outcome reporting. In the stakeholder survey, over 90% of ~4,000 respondents rated clinical outcome measures critically important, but patient-centred outcomes were rated lower, particularly among HCPs. Sixty-seven stakeholders contributed to the Delphi process, which yielded eight core outcomes and four ‘additional important patient-centred’ outcomes from a 64- outcome longlist. Conclusions: Collaborative consensus methodology was used to agree future priorities and outcome measures for APOM research. Both initiatives found areas of close agreement between different stakeholders, while also uncovering some significant differences between HCPs’ and service users’ perspectives. These results highlighted the importance of comprehensive stakeholder participation to avoid missing certain stakeholder viewpoints and maximise relevance of APOM research to all users.
date: 2025-01-28
date_type: published
oa_status: green
full_text_type: other
thesis_class: doctoral_open
thesis_award: Ph.D
language: eng
primo: open
primo_central: open_green
verified: verified_manual
elements_id: 2353780
lyricists_name: Boney, Ritchie
lyricists_id: ROCBO17
actors_name: Boney, Ritchie
actors_name: Kalinowski, Damian
actors_id: ROCBO17
actors_id: DKALI47
actors_role: owner
actors_role: impersonator
full_text_status: public
pages: 303
institution: UCL (University College London)
department: Surgery & Interventional Science
thesis_type: Doctoral
citation:        Boney, Ritchie Oliver Caleb;      (2025)    Improving the quality and patient relevance of perioperative research.                   Doctoral thesis  (Ph.D), UCL (University College London).     Green open access   
 
document_url: https://discovery.ucl.ac.uk/id/eprint/10203603/7/Boney_10203603_Thesis.pdf