TY - JOUR UR - https://doi.org/10.1016/j.mri.2015.12.027 A1 - Liu, Y A1 - Captur, G A1 - Moon, JC A1 - Guo, S A1 - Yang, X A1 - Zhang, S A1 - Li, C Y1 - 2016/06// N2 - This paper presents a new level set method for segmentation of cardiac left and right ventricles. We extend the edge based distance regularized level set evolution (DRLSE) model in Li et al. (2010) to a two-level-set formulation, with the 0-level set and k-level set representing the endocardium and epicardium, respectively. The extraction of endocardium and epicardium is obtained as a result of the interactive curve evolution of the 0 and k level sets derived from the proposed variational level set formulation. The initialization of the level set function in the proposed two-level-set DRLSE model is generated from roughly located endocardium, which can be performed by applying the original DRLSE model. Experimental results have demonstrated the effectiveness of the proposed two-level-set DRLSE model. SP - 699 TI - Distance regularized two level sets for segmentation of left and right ventricles from cine-MRI N1 - This version is the author accepted manuscript. For information on re-use, please refer to the publisher?s terms and conditions. EP - 706 AV - public KW - MRI KW - segmentation KW - two-level-set KW - left and right ventricles ID - discovery10199495 PB - ELSEVIER SCIENCE INC VL - 34 SN - 0730-725X IS - 5 JF - Magnetic Resonance Imaging ER -