eprintid: 10197953 rev_number: 7 eprint_status: archive userid: 699 dir: disk0/10/19/79/53 datestamp: 2024-10-03 07:25:56 lastmod: 2024-10-03 07:25:56 status_changed: 2024-10-03 07:25:56 type: article metadata_visibility: show sword_depositor: 699 creators_name: Poon, Eric KW creators_name: Ninomiya, Kai creators_name: Kageyama, Shigetaka creators_name: Guo, Xiaojing creators_name: Reimers, Bernhard creators_name: Torii, Ryo creators_name: Dijkstra, Jouke creators_name: Bourantas, Christos V creators_name: Reiber, Johan HC creators_name: Barlis, Peter creators_name: Onuma, Yoshinobu creators_name: Serruys, Patrick W title: Two Facets of Shear Stress Post Drug Coating Balloon: Angiography Versus Optical Coherence Tomography Fusion Approach ispublished: pub divisions: UCL divisions: B04 divisions: F45 keywords: Blood viscosity; coronary angiography; hemodynamic; image processing, computer-assisted; tomography, optical coherence note: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions. abstract: A 58-year-old patient with hypertension, dyslipidemia, and typical angina symptoms was referred for a coronary angiogram following a computed tomography coronary angiogram showing a significant stenosis in the left circumflex artery (Figure 1A). This demonstrated moderate stenosis with a minimum lumen diameter (MLD) of 1.2 mm, diameter stenosis of 51%, and a quantitative flow ratio (QFR, Medis Imaging, Leiden, the Netherlands) assessment of 0.80 indicating a flow-limiting stenosis (Figure 1B). The patient was enrolled in the randomized TRANSFORM-I trial (Treatment of Small Coronary Vessels: MagicTouch Sirolimus Coated Balloon, NCT03913832),1 comparing the novel Magic Touch sirolimus-coated balloon (Concept Medical, Surat, India) to the SeQuent Please Neo paclitaxel-coated balloon (B.Braun, Berlin, Germany) in small vessels. The patient received treatment with a 2.5×30 mm SeQuent paclitaxel-coated balloon. The balloon was inflated for 60 s, resulting in an acute gain of 0.60 mm (MLD preprocedure versus MLD postprocedure: 1.20 versus 1.80 mm) and an improved postprocedure QFR of 0.91 (Figure 1C and 1D). The patient underwent optical coherence tomography (OCT) imaging postprocedure, which showed a minimum lumen area of 2.36 mm2 and an area stenosis of 46%, respectively. In addition, OCT revealed a nonflow-limiting dissection 12.6 mm in length (Figure 1E and 1F) that extended to the media with a maximum dissection arc of 153°, and a large dissection volume of 13.8 mm3 (Video S1). date: 2024-04 date_type: published publisher: American Heart Association official_url: http://dx.doi.org/10.1161/circimaging.123.016279 oa_status: green full_text_type: other language: eng primo: open primo_central: open_green verified: verified_manual elements_id: 2262330 doi: 10.1161/CIRCIMAGING.123.016279 medium: Print-Electronic lyricists_name: Torii, Ryo lyricists_id: RTORI16 actors_name: Torii, Ryo actors_id: RTORI16 actors_role: owner funding_acknowledgements: NCT03913832 [The TRANSFORM-I trial (Treatment of Small Coronary Vessels: MagicTouch Sirolimus Coated Balloon)]; [Medical B.V] full_text_status: public publication: Circulation: Cardiovascular Imaging volume: 17 number: 4 article_number: e016279 event_location: United States issn: 1941-9651 citation: Poon, Eric KW; Ninomiya, Kai; Kageyama, Shigetaka; Guo, Xiaojing; Reimers, Bernhard; Torii, Ryo; Dijkstra, Jouke; ... Serruys, Patrick W; + view all <#> Poon, Eric KW; Ninomiya, Kai; Kageyama, Shigetaka; Guo, Xiaojing; Reimers, Bernhard; Torii, Ryo; Dijkstra, Jouke; Bourantas, Christos V; Reiber, Johan HC; Barlis, Peter; Onuma, Yoshinobu; Serruys, Patrick W; - view fewer <#> (2024) Two Facets of Shear Stress Post Drug Coating Balloon: Angiography Versus Optical Coherence Tomography Fusion Approach. Circulation: Cardiovascular Imaging , 17 (4) , Article e016279. 10.1161/CIRCIMAGING.123.016279 <https://doi.org/10.1161/CIRCIMAGING.123.016279>. Green open access document_url: https://discovery.ucl.ac.uk/id/eprint/10197953/1/CIRCCVIM2023016279R1.pdf