eprintid: 10197953
rev_number: 7
eprint_status: archive
userid: 699
dir: disk0/10/19/79/53
datestamp: 2024-10-03 07:25:56
lastmod: 2024-10-03 07:25:56
status_changed: 2024-10-03 07:25:56
type: article
metadata_visibility: show
sword_depositor: 699
creators_name: Poon, Eric KW
creators_name: Ninomiya, Kai
creators_name: Kageyama, Shigetaka
creators_name: Guo, Xiaojing
creators_name: Reimers, Bernhard
creators_name: Torii, Ryo
creators_name: Dijkstra, Jouke
creators_name: Bourantas, Christos V
creators_name: Reiber, Johan HC
creators_name: Barlis, Peter
creators_name: Onuma, Yoshinobu
creators_name: Serruys, Patrick W
title: Two Facets of Shear Stress Post Drug Coating Balloon: Angiography Versus Optical Coherence Tomography Fusion Approach
ispublished: pub
divisions: UCL
divisions: B04
divisions: F45
keywords: Blood viscosity; coronary angiography; 
hemodynamic; image processing, computer-assisted; 
tomography, optical coherence
note: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
abstract: A 58-year-old patient with hypertension, dyslipidemia, and typical angina symptoms was referred for a coronary angiogram following a computed tomography coronary angiogram showing a significant stenosis in the left circumflex artery (Figure 1A). This demonstrated moderate stenosis with a minimum lumen diameter (MLD) of 1.2 mm, diameter stenosis of 51%, and a quantitative flow ratio (QFR, Medis Imaging, Leiden, the Netherlands) assessment of 0.80 indicating a flow-limiting stenosis (Figure 1B). The patient was enrolled in the randomized TRANSFORM-I trial (Treatment of Small Coronary Vessels: MagicTouch Sirolimus Coated Balloon, NCT03913832),1 comparing the novel Magic Touch sirolimus-coated balloon (Concept Medical, Surat, India) to the SeQuent Please Neo paclitaxel-coated balloon (B.Braun, Berlin, Germany) in small vessels. The patient received treatment with a 2.5×30 mm SeQuent paclitaxel-coated balloon. The balloon was inflated for 60 s, resulting in an acute gain of 0.60 mm (MLD preprocedure versus MLD postprocedure: 1.20 versus 1.80 mm) and an improved postprocedure QFR of 0.91 (Figure 1C and 1D). The patient underwent optical coherence tomography (OCT) imaging postprocedure, which showed a minimum lumen area of 2.36 mm2 and an area stenosis of 46%, respectively. In addition, OCT revealed a nonflow-limiting dissection 12.6 mm in length (Figure 1E and 1F) that extended to the media with a maximum dissection arc of 153°, and a large dissection volume of 13.8 mm3 (Video S1).
date: 2024-04
date_type: published
publisher: American Heart Association
official_url: http://dx.doi.org/10.1161/circimaging.123.016279
oa_status: green
full_text_type: other
language: eng
primo: open
primo_central: open_green
verified: verified_manual
elements_id: 2262330
doi: 10.1161/CIRCIMAGING.123.016279
medium: Print-Electronic
lyricists_name: Torii, Ryo
lyricists_id: RTORI16
actors_name: Torii, Ryo
actors_id: RTORI16
actors_role: owner
funding_acknowledgements: NCT03913832 [The TRANSFORM-I trial (Treatment of Small Coronary Vessels: MagicTouch Sirolimus Coated Balloon)]; [Medical B.V]
full_text_status: public
publication: Circulation: Cardiovascular Imaging
volume: 17
number: 4
article_number: e016279
event_location: United States
issn: 1941-9651
citation:        Poon, Eric KW;    Ninomiya, Kai;    Kageyama, Shigetaka;    Guo, Xiaojing;    Reimers, Bernhard;    Torii, Ryo;    Dijkstra, Jouke;                     ... Serruys, Patrick W; + view all <#>        Poon, Eric KW;  Ninomiya, Kai;  Kageyama, Shigetaka;  Guo, Xiaojing;  Reimers, Bernhard;  Torii, Ryo;  Dijkstra, Jouke;  Bourantas, Christos V;  Reiber, Johan HC;  Barlis, Peter;  Onuma, Yoshinobu;  Serruys, Patrick W;   - view fewer <#>    (2024)    Two Facets of Shear Stress Post Drug Coating Balloon: Angiography Versus Optical Coherence Tomography Fusion Approach.                   Circulation: Cardiovascular Imaging , 17  (4)    , Article e016279.  10.1161/CIRCIMAGING.123.016279 <https://doi.org/10.1161/CIRCIMAGING.123.016279>.       Green open access   
 
document_url: https://discovery.ucl.ac.uk/id/eprint/10197953/1/CIRCCVIM2023016279R1.pdf