eprintid: 10196182
rev_number: 15
eprint_status: archive
userid: 699
dir: disk0/10/19/61/82
datestamp: 2024-08-28 08:26:32
lastmod: 2025-01-06 16:43:41
status_changed: 2024-08-28 08:26:32
type: article
metadata_visibility: show
sword_depositor: 699
creators_name: Watt, Fraser
creators_name: Muthurangu, Vivek
creators_name: Steeden, Jennifer
creators_name: Mackle, Eleanor
creators_name: Desjardins, Adrien
creators_name: Zhang, Edward
creators_name: Beard, Paul
creators_name: Alles, Erwin
title: Multimodal Optical Ultrasound Imaging: Real-Time Imaging Under Concurrent CT or MRI
ispublished: pub
divisions: UCL
divisions: B04
divisions: F42
keywords: Ultrasound, Electromagnetism, Fiber optic devices, Optical fibers, Computed tomography, Medical diagnosis, Magnetic resonance imaging, Ultrasonography
note: © 2024 Author(s). All article content, except where otherwise noted, is licensed under a Creative Commons Attribution (CC BY) license
(https://creativecommons.org/licenses/by/4.0/). https://doi.org/10.1063/5.0225554
abstract: Optical ultrasound (OpUS) imaging is an ultrasound modality that utilizes fiber-optic ultrasound sources and detectors to perform pulse-echo ultrasound imaging. These probes can be constructed entirely from glass optical fibers and plastic components, and as such, these devices have been predicted to be compatible with computed tomography (CT) and magnetic resonance imaging (MRI), modalities that use intense electromagnetic fields for imaging. However, to date, this compatibility has not been demonstrated. In this work, a free-hand OpUS imaging system was developed specifically to investigate the compatibility of OpUS systems with CT and MRI imaging systems. The OpUS imaging platform discussed in this work was used to perform real-time OpUS imaging under (separately) concurrent CT and MRI. CT and MRI imaging of the OpUS probe was used to determine if the probe itself would induce artifacts in the CT and MRI imaging, and ultrasound resolution targets and background measurements were used to assess any impact of CT and MRI on the OpUS signal fidelity. These measurements demonstrate that there was negligible interaction between the OpUS system and both the CT and MRI systems, and to further demonstrate this capability, concurrent OpUS-CT and OpUS-MRI imaging was conducted of a tissue-mimicking phantom and a dynamic motion phantom. This work presents a comprehensive demonstration of an OpUS imaging system operating alongside CT and MRI, which opens up new applications of ultrasound imaging in electromagnetically challenging settings.
date: 2024-09-30
date_type: published
publisher: AIP Publishing LLC
official_url: https://doi.org/10.1063/5.0225554
oa_status: green
full_text_type: pub
language: eng
primo: open
primo_central: open_green
verified: verified_manual
elements_id: 2307294
doi: 10.1063/5.0225554
lyricists_name: Watt, Fraser
lyricists_id: FWATT83
actors_name: Watt, Fraser
actors_id: FWATT83
actors_role: owner
funding_acknowledgements: 203145Z/16/Z [Wellcome/EPSRC centre for Interventional and Surgical Sciences (WEISS)]; EP/T5177931 [Engineering and Physical Sciences Research Council]; PGS19-2/10006 [Rosetrees Trust]; SBF007/100006 [Academy of Medical Sciences]; 741149 [European Research Council]; MR/S032290/1 [UK Research and Innovation]
full_text_status: public
publication: APL Photonics
volume: 9
number: 9
article_number: 096103
issn: 2378-0967
citation:        Watt, Fraser;    Muthurangu, Vivek;    Steeden, Jennifer;    Mackle, Eleanor;    Desjardins, Adrien;    Zhang, Edward;    Beard, Paul;           Watt, Fraser;  Muthurangu, Vivek;  Steeden, Jennifer;  Mackle, Eleanor;  Desjardins, Adrien;  Zhang, Edward;  Beard, Paul;  Alles, Erwin;   - view fewer <#>    (2024)    Multimodal Optical Ultrasound Imaging: Real-Time Imaging Under Concurrent CT or MRI.                   APL Photonics , 9  (9)    , Article 096103.  10.1063/5.0225554 <https://doi.org/10.1063/5.0225554>.       Green open access   
 
document_url: https://discovery.ucl.ac.uk/id/eprint/10196182/13/Watt_096103_1_5.0225554.pdf