TY - JOUR KW - Ultrasound KW - Electromagnetism KW - Fiber optic devices KW - Optical fibers KW - Computed tomography KW - Medical diagnosis KW - Magnetic resonance imaging KW - Ultrasonography TI - Multimodal Optical Ultrasound Imaging: Real-Time Imaging Under Concurrent CT or MRI UR - https://doi.org/10.1063/5.0225554 JF - APL Photonics AV - public ID - discovery10196182 N1 - © 2024 Author(s). All article content, except where otherwise noted, is licensed under a Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). https://doi.org/10.1063/5.0225554 SN - 2378-0967 VL - 9 PB - AIP Publishing LLC Y1 - 2024/09/30/ A1 - Watt, Fraser A1 - Muthurangu, Vivek A1 - Steeden, Jennifer A1 - Mackle, Eleanor A1 - Desjardins, Adrien A1 - Zhang, Edward A1 - Beard, Paul A1 - Alles, Erwin IS - 9 N2 - Optical ultrasound (OpUS) imaging is an ultrasound modality that utilizes fiber-optic ultrasound sources and detectors to perform pulse-echo ultrasound imaging. These probes can be constructed entirely from glass optical fibers and plastic components, and as such, these devices have been predicted to be compatible with computed tomography (CT) and magnetic resonance imaging (MRI), modalities that use intense electromagnetic fields for imaging. However, to date, this compatibility has not been demonstrated. In this work, a free-hand OpUS imaging system was developed specifically to investigate the compatibility of OpUS systems with CT and MRI imaging systems. The OpUS imaging platform discussed in this work was used to perform real-time OpUS imaging under (separately) concurrent CT and MRI. CT and MRI imaging of the OpUS probe was used to determine if the probe itself would induce artifacts in the CT and MRI imaging, and ultrasound resolution targets and background measurements were used to assess any impact of CT and MRI on the OpUS signal fidelity. These measurements demonstrate that there was negligible interaction between the OpUS system and both the CT and MRI systems, and to further demonstrate this capability, concurrent OpUS-CT and OpUS-MRI imaging was conducted of a tissue-mimicking phantom and a dynamic motion phantom. This work presents a comprehensive demonstration of an OpUS imaging system operating alongside CT and MRI, which opens up new applications of ultrasound imaging in electromagnetically challenging settings. ER -