eprintid: 10195969 rev_number: 7 eprint_status: archive userid: 699 dir: disk0/10/19/59/69 datestamp: 2024-08-20 09:05:50 lastmod: 2024-08-20 09:05:50 status_changed: 2024-08-20 09:05:50 type: article metadata_visibility: show sword_depositor: 699 creators_name: Zhang, Xuehuan creators_name: Guo, Liwei creators_name: Yang, Yuting creators_name: Wang, Shuangjing creators_name: Wei, Linyang creators_name: Wu, Mingwei creators_name: Ventikos, Yiannis creators_name: Xiong, Jiang creators_name: Chen, Duanduan title: The necessity evaluation of distal bare stent for treating type B aortic dissection using image-based computational flow analysis ispublished: pub divisions: UCL divisions: B04 divisions: F45 keywords: Image processing, Computational fluid dynamics, Haemodynamics, Pathology, Cardiovascular system note: This version is the version of record. For information on re-use, please refer to the publisher’s terms and conditions. abstract: This study aims to verify the necessity of the provisional extension to induce complete attachment (PETTICOAT) technique, by comparing the clinical outcomes with traditional thoracic endovascular repair (TEVAR) procedure. 40 patients with a total of 120 computed tomography angiography examinations (including Pre, Post1, and Post2 for each case) were included and divided into PETTICOAT group (n = 20) and TEVAR group (n = 20) according to the employed intervention technique. The potential risk factors for distal stent-induced new entry (SINE) and morphological and hemodynamic indices related to the aortic remodeling were computed and compared between two groups. All computed potential risk factors for distal SINE showed insignificant difference between PETTICOAT and TEVAR groups. There is no statistically significant difference in the morphological parameters when assessing the aortic remodeling. Regarding hemodynamic factors, the percentage of high relative residence time of Post2 was greater in PETTICOAT group than that of TEVAR group (median, 0.22; interquartile range (IQR), [0.00–0.56] in PETTICOAT vs median, 0.01; IQR, [0.00–0.10] in TEVAR; p = 0.01). The first balance position of computed luminal pressure difference shifted more distally from Post1 to Post2 for patients underwent PETTICOAT than those underwent TEVAR (median, 1.04 cm; IQR, [0.00–6.29 cm] in PETTICOAT vs median, 0.00 cm; IQR, [−1.66 to 1.28 cm] in TEVAR; p = 0.02). PETTICOAT procedure could effectively enhance false lumen thrombosis and aortic remodeling when assessed from functional perspective. However, there is a lack of evidence to support that PETTICOAT can prevent distal SINE. date: 2024-08 date_type: published publisher: AIP Publishing official_url: https://doi.org/10.1063/5.0215846 full_text_type: pub language: eng verified: verified_manual elements_id: 2306166 doi: 10.1063/5.0215846 lyricists_name: Guo, Liwei lyricists_id: LGUOX16 actors_name: Flynn, Bernadette actors_id: BFFLY94 actors_role: owner full_text_status: restricted publication: Physics of Fluids volume: 36 number: 8 article_number: 081905 issn: 1070-6631 citation: Zhang, Xuehuan; Guo, Liwei; Yang, Yuting; Wang, Shuangjing; Wei, Linyang; Wu, Mingwei; Ventikos, Yiannis; ... Chen, Duanduan; + view all <#> Zhang, Xuehuan; Guo, Liwei; Yang, Yuting; Wang, Shuangjing; Wei, Linyang; Wu, Mingwei; Ventikos, Yiannis; Xiong, Jiang; Chen, Duanduan; - view fewer <#> (2024) The necessity evaluation of distal bare stent for treating type B aortic dissection using image-based computational flow analysis. Physics of Fluids , 36 (8) , Article 081905. 10.1063/5.0215846 <https://doi.org/10.1063/5.0215846>. document_url: https://discovery.ucl.ac.uk/id/eprint/10195969/1/081905_1_5.0215846.pdf