<> <http://www.w3.org/2000/01/rdf-schema#comment> "The repository administrator has not yet configured an RDF license."^^<http://www.w3.org/2001/XMLSchema#string> .
<> <http://xmlns.com/foaf/0.1/primaryTopic> <https://discovery.ucl.ac.uk/id/eprint/10193544> .
<https://discovery.ucl.ac.uk/id/eprint/10193544> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://purl.org/ontology/bibo/AcademicArticle> .
<https://discovery.ucl.ac.uk/id/eprint/10193544> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://purl.org/ontology/bibo/Article> .
<https://discovery.ucl.ac.uk/id/eprint/10193544> <http://purl.org/dc/terms/title> "A geranylated chalcone with antiplatelet activity from the leaves of breadfruit (Artocarpus altilis)"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/eprint/10193544> <http://purl.org/ontology/bibo/abstract> "Platelet plays a crucial role in cardiovascular diseases (CVDs) development. Abnormalities in platelet aggregation provokes thromboembolism, eventually leading to death. In Indonesia, breadfruit (Artocarpus altilis) leaf is traditionally used to treat CVDs. This study aimed to evaluate the antiplatelet activity of A. altilis leaf extract (AAE) and to identify its active compound. A. altilis leaves were extracted with ethanol, and the antiplatelet activity was assessed using ADP-induced platelet aggregation. The major compound was isolated with column chromatography followed by preparative TLC, and the structure was determined on the basis of UV, MS, IR, and NMR spectra. The binding mode of the active compound to platelet receptors was characterized in in silico study. AAE exhibited an antiplatelet activity (IC50 of 252.23 µg/mL). A geranylated chalcone, 2-geranyl-2ʹ,3,3,4ʹ-tetrahydroxydihydrochalcone (GTDC) was identified as the antiplatelet compound (IC50 of 9.09 µM). GTDC actions with P2Y12 platelet receptor involving three amino acid residues."^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/eprint/10193544> <http://purl.org/dc/terms/date> "2020-10-02" .
<https://discovery.ucl.ac.uk/id/document/1753586> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://purl.org/ontology/bibo/Document> .
<https://discovery.ucl.ac.uk/id/eprint/10193544> <http://purl.org/ontology/bibo/volume> "67" .
<https://discovery.ucl.ac.uk/id/eprint/10193544> <http://purl.org/ontology/bibo/issue> "4" .
<https://discovery.ucl.ac.uk/id/org/ext-441e40b31e72eae3a430dd1d101522d5> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Organization> .
<https://discovery.ucl.ac.uk/id/org/ext-441e40b31e72eae3a430dd1d101522d5> <http://xmlns.com/foaf/0.1/name> "Pensoft Publishers"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/eprint/10193544> <http://purl.org/dc/terms/publisher> <https://discovery.ucl.ac.uk/id/org/ext-441e40b31e72eae3a430dd1d101522d5> .
<https://discovery.ucl.ac.uk/id/publication/ext-04280296> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://purl.org/ontology/bibo/Collection> .
<https://discovery.ucl.ac.uk/id/publication/ext-04280296> <http://xmlns.com/foaf/0.1/name> "Pharmacia"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/eprint/10193544> <http://purl.org/dc/terms/isPartOf> <https://discovery.ucl.ac.uk/id/publication/ext-04280296> .
<https://discovery.ucl.ac.uk/id/publication/ext-04280296> <http://www.w3.org/2002/07/owl#sameAs> <urn:issn:04280296> .
<https://discovery.ucl.ac.uk/id/publication/ext-04280296> <http://purl.org/ontology/bibo/issn> "04280296" .
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<https://discovery.ucl.ac.uk/id/eprint/10193544> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10193544#authors> .
<https://discovery.ucl.ac.uk/id/eprint/10193544#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_1> <https://discovery.ucl.ac.uk/id/person/ext-9d277377e68af2aff0d5de83a7775595> .
<https://discovery.ucl.ac.uk/id/eprint/10193544> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-ecd738afb0c0b2f054dda5af151154e0> .
<https://discovery.ucl.ac.uk/id/eprint/10193544> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10193544#authors> .
<https://discovery.ucl.ac.uk/id/eprint/10193544#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_2> <https://discovery.ucl.ac.uk/id/person/ext-ecd738afb0c0b2f054dda5af151154e0> .
<https://discovery.ucl.ac.uk/id/eprint/10193544> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-c1e418720d72180cf74ed9e24957f9cf> .
<https://discovery.ucl.ac.uk/id/eprint/10193544> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10193544#authors> .
<https://discovery.ucl.ac.uk/id/eprint/10193544#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_3> <https://discovery.ucl.ac.uk/id/person/ext-c1e418720d72180cf74ed9e24957f9cf> .
<https://discovery.ucl.ac.uk/id/eprint/10193544> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-6cf0898bf13f80ddd927ae564e89b5da> .
<https://discovery.ucl.ac.uk/id/eprint/10193544> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10193544#authors> .
<https://discovery.ucl.ac.uk/id/eprint/10193544#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_4> <https://discovery.ucl.ac.uk/id/person/ext-6cf0898bf13f80ddd927ae564e89b5da> .
<https://discovery.ucl.ac.uk/id/eprint/10193544> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-2d63551b63dd223092cc1b7b2f9c1b28> .
<https://discovery.ucl.ac.uk/id/eprint/10193544> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10193544#authors> .
<https://discovery.ucl.ac.uk/id/eprint/10193544#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_5> <https://discovery.ucl.ac.uk/id/person/ext-2d63551b63dd223092cc1b7b2f9c1b28> .
<https://discovery.ucl.ac.uk/id/eprint/10193544> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-7fda1547f72bd7b72c7d5056b64eedc5> .
<https://discovery.ucl.ac.uk/id/eprint/10193544> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10193544#authors> .
<https://discovery.ucl.ac.uk/id/eprint/10193544#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_6> <https://discovery.ucl.ac.uk/id/person/ext-7fda1547f72bd7b72c7d5056b64eedc5> .
<https://discovery.ucl.ac.uk/id/eprint/10193544> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-9634e28513154e093b7f9c62b40fde78> .
<https://discovery.ucl.ac.uk/id/eprint/10193544> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10193544#authors> .
<https://discovery.ucl.ac.uk/id/eprint/10193544#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_7> <https://discovery.ucl.ac.uk/id/person/ext-9634e28513154e093b7f9c62b40fde78> .
<https://discovery.ucl.ac.uk/id/eprint/10193544> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-b96a1c6f65390f0b6d7a98ccd6867a3d> .
<https://discovery.ucl.ac.uk/id/eprint/10193544> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10193544#authors> .
<https://discovery.ucl.ac.uk/id/eprint/10193544#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_8> <https://discovery.ucl.ac.uk/id/person/ext-b96a1c6f65390f0b6d7a98ccd6867a3d> .
<https://discovery.ucl.ac.uk/id/eprint/10193544> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-a414304ef52776bbbcb5b5892b4367b2> .
<https://discovery.ucl.ac.uk/id/eprint/10193544> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10193544#authors> .
<https://discovery.ucl.ac.uk/id/eprint/10193544#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_9> <https://discovery.ucl.ac.uk/id/person/ext-a414304ef52776bbbcb5b5892b4367b2> .
<https://discovery.ucl.ac.uk/id/person/ext-9d277377e68af2aff0d5de83a7775595> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery.ucl.ac.uk/id/person/ext-9d277377e68af2aff0d5de83a7775595> <http://xmlns.com/foaf/0.1/givenName> "Nanang"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-9d277377e68af2aff0d5de83a7775595> <http://xmlns.com/foaf/0.1/familyName> "Fakhrudin"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-9d277377e68af2aff0d5de83a7775595> <http://xmlns.com/foaf/0.1/name> "Nanang Fakhrudin"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-9634e28513154e093b7f9c62b40fde78> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery.ucl.ac.uk/id/person/ext-9634e28513154e093b7f9c62b40fde78> <http://xmlns.com/foaf/0.1/givenName> "Ari"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-9634e28513154e093b7f9c62b40fde78> <http://xmlns.com/foaf/0.1/familyName> "Sudarmanto"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-9634e28513154e093b7f9c62b40fde78> <http://xmlns.com/foaf/0.1/name> "Ari Sudarmanto"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-2d63551b63dd223092cc1b7b2f9c1b28> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery.ucl.ac.uk/id/person/ext-2d63551b63dd223092cc1b7b2f9c1b28> <http://xmlns.com/foaf/0.1/givenName> "Arief"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-2d63551b63dd223092cc1b7b2f9c1b28> <http://xmlns.com/foaf/0.1/familyName> "Nurrochmad"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-2d63551b63dd223092cc1b7b2f9c1b28> <http://xmlns.com/foaf/0.1/name> "Arief Nurrochmad"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-c1e418720d72180cf74ed9e24957f9cf> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery.ucl.ac.uk/id/person/ext-c1e418720d72180cf74ed9e24957f9cf> <http://xmlns.com/foaf/0.1/givenName> "Marce Inggrita"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-c1e418720d72180cf74ed9e24957f9cf> <http://xmlns.com/foaf/0.1/familyName> "Takubessi"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-c1e418720d72180cf74ed9e24957f9cf> <http://xmlns.com/foaf/0.1/name> "Marce Inggrita Takubessi"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-ecd738afb0c0b2f054dda5af151154e0> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery.ucl.ac.uk/id/person/ext-ecd738afb0c0b2f054dda5af151154e0> <http://xmlns.com/foaf/0.1/givenName> "Krisna Kharisma"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-ecd738afb0c0b2f054dda5af151154e0> <http://xmlns.com/foaf/0.1/familyName> "Pertiwi"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-ecd738afb0c0b2f054dda5af151154e0> <http://xmlns.com/foaf/0.1/name> "Krisna Kharisma Pertiwi"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-a414304ef52776bbbcb5b5892b4367b2> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery.ucl.ac.uk/id/person/ext-a414304ef52776bbbcb5b5892b4367b2> <http://xmlns.com/foaf/0.1/givenName> "Subagus"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-a414304ef52776bbbcb5b5892b4367b2> <http://xmlns.com/foaf/0.1/familyName> "Wahyuono"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-a414304ef52776bbbcb5b5892b4367b2> <http://xmlns.com/foaf/0.1/name> "Subagus Wahyuono"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-b96a1c6f65390f0b6d7a98ccd6867a3d> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery.ucl.ac.uk/id/person/ext-b96a1c6f65390f0b6d7a98ccd6867a3d> <http://xmlns.com/foaf/0.1/givenName> "Arief Adi"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-b96a1c6f65390f0b6d7a98ccd6867a3d> <http://xmlns.com/foaf/0.1/familyName> "Nugroho"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-b96a1c6f65390f0b6d7a98ccd6867a3d> <http://xmlns.com/foaf/0.1/name> "Arief Adi Nugroho"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-6cf0898bf13f80ddd927ae564e89b5da> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery.ucl.ac.uk/id/person/ext-6cf0898bf13f80ddd927ae564e89b5da> <http://xmlns.com/foaf/0.1/givenName> "Eka Fitri"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-6cf0898bf13f80ddd927ae564e89b5da> <http://xmlns.com/foaf/0.1/familyName> "Susiani"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-6cf0898bf13f80ddd927ae564e89b5da> <http://xmlns.com/foaf/0.1/name> "Eka Fitri Susiani"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-7fda1547f72bd7b72c7d5056b64eedc5> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery.ucl.ac.uk/id/person/ext-7fda1547f72bd7b72c7d5056b64eedc5> <http://xmlns.com/foaf/0.1/givenName> "Sitarina"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-7fda1547f72bd7b72c7d5056b64eedc5> <http://xmlns.com/foaf/0.1/familyName> "Widyarini"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-7fda1547f72bd7b72c7d5056b64eedc5> <http://xmlns.com/foaf/0.1/name> "Sitarina Widyarini"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/eprint/10193544> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://eprints.org/ontology/EPrint> .
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<https://discovery.ucl.ac.uk/id/eprint/10193544> <http://eprints.org/ontology/hasDocument> <https://discovery.ucl.ac.uk/id/document/1753587> .
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<https://discovery.ucl.ac.uk/id/eprint/10193544> <http://eprints.org/ontology/hasDocument> <https://discovery.ucl.ac.uk/id/document/1753588> .
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