TY  - INPR
N1  - © 2024 The Authors. Magnetic Resonance in Medicine published by Wiley Periodicals LLC on behalf of International Society for Magnetic Resonance in Medicine.

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KW  - T1 mapping
KW  -  inversion recovery
KW  -  open data
KW  -  quantitative MRI
KW  -  reproducibility
PB  - Wiley
A1  - Boudreau, Mathieu
A1  - Karakuzu, Agah
A1  - Cohen-Adad, Julien
A1  - Bozkurt, Ecem
A1  - Carr, Madeline
A1  - Castellaro, Marco
A1  - Concha, Luis
A1  - Doneva, Mariya
A1  - Dual, Seraina A
A1  - Ensworth, Alex
A1  - Foias, Alexandru
A1  - Fortier, Véronique
A1  - Gabr, Refaat E
A1  - Gilbert, Guillaume
A1  - Glide-Hurst, Carri K
A1  - Grech-Sollars, Matthew
A1  - Hu, Siyuan
A1  - Jalnefjord, Oscar
A1  - Jovicich, Jorge
A1  - Keskin, Kübra
A1  - Koken, Peter
A1  - Kolokotronis, Anastasia
A1  - Kukran, Simran
A1  - Lee, Nam G
A1  - Levesque, Ives R
A1  - Li, Bochao
A1  - Ma, Dan
A1  - Mädler, Burkhard
A1  - Maforo, Nyasha G
A1  - Near, Jamie
A1  - Pasaye, Erick
A1  - Ramirez-Manzanares, Alonso
A1  - Statton, Ben
A1  - Stehning, Christian
A1  - Tambalo, Stefano
A1  - Tian, Ye
A1  - Wang, Chenyang
A1  - Weiss, Kilian
A1  - Zakariaei, Niloufar
A1  - Zhang, Shuo
A1  - Zhao, Ziwei
A1  - Stikov, Nikola
A1  - ISMRM Reproducible Research Study Group and the ISMRM Quantitati
JF  - Magnetic Resonance in Medicine
AV  - public
TI  - Repeat it without me: Crowdsourcing the T1 mapping common ground via the ISMRM reproducibility challenge
Y1  - 2024/05/10/
SN  - 0740-3194
UR  - http://dx.doi.org/10.1002/mrm.30111
ID  - discovery10192414
N2  - PURPOSE: T1 mapping is a widely used quantitative MRI technique, but its tissue-specific values remain inconsistent across protocols, sites, and vendors. The ISMRM Reproducible Research and Quantitative MR study groups jointly launched a challenge to assess the reproducibility of a well-established inversion-recovery T1 mapping technique, using acquisition details from a seminal T1 mapping paper on a standardized phantom and in human brains. METHODS: The challenge used the acquisition protocol from Barral et al. (2010). Researchers collected T1 mapping data on the ISMRM/NIST phantom and/or in human brains. Data submission, pipeline development, and analysis were conducted using open-source platforms. Intersubmission and intrasubmission comparisons were performed. RESULTS: Eighteen submissions (39 phantom and 56 human datasets) on scanners by three MRI vendors were collected at 3?T (except one, at 0.35?T). The mean coefficient of variation was 6.1% for intersubmission phantom measurements, and 2.9% for intrasubmission measurements. For humans, the intersubmission/intrasubmission coefficient of variation was 5.9/3.2% in the genu and 16/6.9% in the cortex. An interactive dashboard for data visualization was also developed: https://rrsg2020.dashboards.neurolibre.org. CONCLUSION: The T1 intersubmission variability was twice as high as the intrasubmission variability in both phantoms and human brains, indicating that the acquisition details in the original paper were insufficient to reproduce a quantitative MRI protocol. This study reports the inherent uncertainty in T1 measures across independent research groups, bringing us one step closer to a practical clinical baseline of T1 variations in vivo.
ER  -