eprintid: 10192143 rev_number: 6 eprint_status: archive userid: 699 dir: disk0/10/19/21/43 datestamp: 2024-05-13 13:59:10 lastmod: 2024-05-13 13:59:10 status_changed: 2024-05-13 13:59:10 type: article metadata_visibility: show sword_depositor: 699 creators_name: Philip, Keir EJ creators_name: Buttery, Sara C creators_name: Bowen, Sarah creators_name: Lewis, Adam creators_name: Jeffery, Edmund creators_name: Alghamdi, Saeed M creators_name: Williams, Parris creators_name: Alasmari, Ali M creators_name: Alsulayyim, Abdullah S creators_name: Orton, Christopher M creators_name: Conway, Francesca creators_name: Chan, Ley creators_name: Vijayakumar, Bavithra creators_name: Tana, Anand creators_name: Tonkin, James creators_name: Perkins, Alexis creators_name: Garner, Justin L creators_name: Srikanthan, Karthikan creators_name: Sadaka, Ahmed creators_name: Pavitt, Matthew J creators_name: Banya, Winston creators_name: Lound, Adam creators_name: Elkin, Sarah creators_name: Polkey, Michael I creators_name: Man, William D-C creators_name: Lewis, Keir creators_name: Cave, Phoene creators_name: Fancourt, Daisy creators_name: Hopkinson, Nicholas S title: Singing for lung health in COPD: a multicentre randomised controlled trial of online delivery ispublished: pub divisions: UCL divisions: B02 divisions: D12 divisions: J96 keywords: Complementary Medicine, Emphysema, Exercise, Pulmonary Rehabilitation, Respiratory Muscles, Humans, Pulmonary Disease, Chronic Obstructive, Female, Male, Middle Aged, Quality of Life, Aged, Singing, Treatment Outcome, Lung, Forced Expiratory Volume, Breathing Exercises, Single-Blind Method note: This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third-party material in this article are included in the Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ abstract: BACKGROUND: Singing for lung health (SLH) is an arts-based breathing control and movement intervention for people with long-term respiratory conditions, intended to improve symptoms and quality of life. Online, remotely delivered programmes might improve accessibility; however, no previous studies have assessed the effectiveness of this approach. METHODS: We conducted an assessor-blind randomised controlled trial comparing the impact of 12 weeks of once-weekly online SLH sessions against usual care on health-related quality of life, assessed using the RAND 36-Item Short Form Health Survey (SF-36) Mental Health Composite (MHC) and Physical Health Composite (PHC) scores. RESULTS: We enrolled 115 people with stable chronic obstructive pulmonary disease (COPD), median (IQR) age 69 (62-74), 56.5% females, 80% prior pulmonary rehabilitation, Medical Research Council dyspnoea scale 4 (3-4), forced expiratory volume in 1 s % predicted 49 (35-63). 50 participants in each arm completed the study. The intervention arm experienced improvements in physical but not mental health components of RAND SF-36; PHC (regression coefficient (95% CI): 1.77 (95% CI 0.11 to 3.44); p=0.037), but not MHC (0.86 (95% CI -1.68 to 3.40); p=0.504). A prespecified responder analysis based on achieving a 10% improvement from baseline demonstrated a response rate for PHC of 32% in the SLH arm and 12.7% for usual care (p=0.024). A between-group difference in responder rate was not found in relation to the MHC (19.3% vs 25.9%; p=0.403). DISCUSSION AND CONCLUSION: A 12-week online SLH programme can improve the physical component of quality of life for people with COPD, but the overall effect is relatively modest compared with the impact seen in research using face-to-face group sessions. Further work on the content, duration and dose of online interventions may be useful. TRIAL REGISTRATION NUMBER: NCT04034212. date: 2024-05-02 date_type: published publisher: BMJ official_url: http://dx.doi.org/10.1136/bmjresp-2024-002365 oa_status: green full_text_type: pub language: eng primo: open primo_central: open_green verified: verified_manual elements_id: 2273908 doi: 10.1136/bmjresp-2024-002365 medium: Electronic pii: 11/1/e002365 lyricists_name: Fancourt, Daisy lyricists_id: DFANC73 actors_name: Flynn, Bernadette actors_id: BFFLY94 actors_role: owner funding_acknowledgements: [Imperial College London]; DF was supported by the Wellcome Trust (205407/Z/1 [Wellcome Trust] full_text_status: public publication: BMJ Open Respiratory Research volume: 11 number: 1 article_number: e002365 event_location: England citation: Philip, Keir EJ; Buttery, Sara C; Bowen, Sarah; Lewis, Adam; Jeffery, Edmund; Alghamdi, Saeed M; Williams, Parris; ... Hopkinson, Nicholas S; + view all <#> Philip, Keir EJ; Buttery, Sara C; Bowen, Sarah; Lewis, Adam; Jeffery, Edmund; Alghamdi, Saeed M; Williams, Parris; Alasmari, Ali M; Alsulayyim, Abdullah S; Orton, Christopher M; Conway, Francesca; Chan, Ley; Vijayakumar, Bavithra; Tana, Anand; Tonkin, James; Perkins, Alexis; Garner, Justin L; Srikanthan, Karthikan; Sadaka, Ahmed; Pavitt, Matthew J; Banya, Winston; Lound, Adam; Elkin, Sarah; Polkey, Michael I; Man, William D-C; Lewis, Keir; Cave, Phoene; Fancourt, Daisy; Hopkinson, Nicholas S; - view fewer <#> (2024) Singing for lung health in COPD: a multicentre randomised controlled trial of online delivery. BMJ Open Respiratory Research , 11 (1) , Article e002365. 10.1136/bmjresp-2024-002365 <https://doi.org/10.1136/bmjresp-2024-002365>. Green open access document_url: https://discovery.ucl.ac.uk/id/eprint/10192143/1/e002365.full.pdf