TY  - INPR
A1  - Singh, Dave
A1  - Han, MeiLan K
A1  - Hawkins, Nathaniel M
A1  - Hurst, John R
A1  - Kocks, Janwillem WH
A1  - Skolnik, Neil
A1  - Stolz, Daiana
A1  - El Khoury, Jad
A1  - Gale, Chris P
KW  - Cardiopulmonary risk
KW  -  Cardiovascular disease
KW  -  Chronic obstructive pulmonary disease
KW  -  Exacerbation
KW  -  Inhaled therapy
KW  -  Mortality
ID  - discovery10191837
AV  - public
TI  - Implications of Cardiopulmonary Risk for the Management of COPD: A Narrative Review
N1  - © 2024 Springer Nature. This article is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/).
JF  - Advances in Therapy
Y1  - 2024/04/25/
UR  - http://dx.doi.org/10.1007/s12325-024-02855-4
PB  - Springer Science and Business Media LLC
N2  - Chronic obstructive pulmonary disease (COPD) constitutes a major global health burden and is the third leading cause of death worldwide. A high proportion of patients with COPD have cardiovascular disease, but there is also evidence that COPD is a risk factor for adverse outcomes in cardiovascular disease. Patients with COPD frequently die of respiratory and cardiovascular causes, yet the identification and management of cardiopulmonary risk remain suboptimal owing to limited awareness and clinical intervention. Acute exacerbations punctuate the progression of COPD in many patients, reducing lung function and increasing the risk of subsequent exacerbations and cardiovascular events that may lead to early death. This narrative review defines and summarises the principles of COPD-associated cardiopulmonary risk, and examines respiratory interventions currently available to modify this risk, as well as providing expert opinion on future approaches to addressing cardiopulmonary risk.
ER  -