@article{discovery10191359, note = {This version is the author accepted manuscript. For information on re-use, please refer to the publisher's terms and conditions.}, publisher = {Elsevier BV}, month = {March}, year = {2024}, title = {The Impact of Excluding Adverse Neonatal Outcomes on the Creation of Gestational Weight Gain Charts Among Women from Low- and Middle-income Countries with Normal and Overweight BMI}, journal = {The American Journal of Clinical Nutrition}, author = {Rangel Bousquet Carrilho, T and Wang, D and Hutcheon, JA and Wang, M and Fawzi, WW and Kac, G and Accrombessi, M and Adu-Afarwuah, S and Alves, JG and Leal de Ara{\'u}jo, CA and Arifeen, S and Artes, R and Ashorn, P and Ashorn, U and Assefa, N and Ayoola, OO and Azizi, F and Bawah, AT and Behboudi-Gandevani, S and Berhane, Y and Bernstein, R and Bhutta, Z and Briand, V and Calvo, EB and Cardoso, MA and Cheng, Y and Chico-Barba, G and Clayton, PE and Collins, SM and Costello, AM and Cruickshank, JK and Devakumar, D and Dewey, KG and Dwarkanath, P and Estrada-Gutierrez, G and Fair, FJ and Farias, DR and Friis, H and Ghosh, S and Girard, AW and Gomo, E and Gondwe, A and Hallamaa, L and Hambidge, KM and Hussein, H and Huybregts, L and Iqbal, R and Katz, J and Khatry, SK and Kolsteren, P and Krebs, NF and Kulmala, T and Kumar, P and Kurpad, AV and Lachat, C and Lartey, A and Lauer, JM and Li, Q and Lipoeto, NI and L{\'o}pez, LB and Loy, SL and Maiya, GA and Maleta, K and Malta, MB and Manandhar, DS and Mangani, C and Mart{\'i}nez-Rojano, H and Martin-Prevel, Y and Martorell, R and Matias, SL and McClure, EM and Melse-Boonstra, A and Miller, JD and Mohamad, M and Jan Mohamed, HJ and Moore, S and Mosquera, PS and Mridha, MK and Munim, S and Mu{\~n}oz-Manrique, C and Natamba, BK and Ome-Kaius, M and Osrin, D and Perichart-Perera, O and Prentice, AM and Ramachandra, P and Ramakrishnan, U and Rivera, J and Roberfroid, D and Rodrigues, PL and Rodr{\'i}guez-Cano, A and Rogerson, SJ and Rond{\'o}, PH and S{\'a}mano, R and Saville, NM and Shivalli, S and Shrestha, BP and Shrestha, R and Roberto da Silva J{\'u}nior, J and Soltani, H}, url = {http://dx.doi.org/10.1016/j.ajcnut.2024.03.016}, abstract = {Background: Existing gestational weight gain (GWG) charts vary considerably in their choice of exclusion/inclusion criteria, and it is unclear to what extent these criteria create differences in the charts' percentile values. // Objectives: We aimed to establish the impact of including/excluding pregnancies with adverse neonatal outcomes when constructing GWG charts. // Methods: This is an individual participant data analysis from 31 studies from low- and middle-income countries. We created a dataset that included all participants and a dataset restricted to those with no adverse neonatal outcomes: preterm {\ensuremath{<}} 37 wk, small or large for gestational age, low birth weight {\ensuremath{<}} 2500 g, or macrosomia {\ensuremath{>}} 4000 g. Quantile regression models were used to create GWG curves from 9 to 40 wk, stratified by prepregnancy BMI, in each dataset. // Results: The dataset without the exclusion criteria applied included 14,685 individuals with normal weight and 4831 with overweight. After removing adverse neonatal outcomes, 10,479 individuals with normal weight and 3466 individuals with overweight remained. GWG distributions at 13, 27, and 40 wk were virtually identical between the datasets with and without the exclusion criteria, except at 40 wk for normal weight and 27 wk for overweight. For the 10th and 90th percentiles, the differences between the estimated GWG were larger for overweight ({$\sim$}1.5 kg) compared with normal weight ({\ensuremath{<}}1 kg). Removal of adverse neonatal outcomes had minimal impact on GWG trajectories of normal weight. For overweight, the percentiles estimated in the dataset without the criteria were slightly higher than those in the dataset with the criteria applied. Nevertheless, differences were {\ensuremath{<}}1 kg and virtually nonexistent at the end of pregnancy. // Conclusions: Removing pregnancies with adverse neonatal outcomes has little or no influence on the GWG trajectories of individuals with normal and overweight.}, issn = {0002-9165}, keywords = {Gestational weight gain; reference; standards; adverse neonatal outcomes} }