eprintid: 10191334
rev_number: 7
eprint_status: archive
userid: 699
dir: disk0/10/19/13/34
datestamp: 2024-04-26 12:10:34
lastmod: 2024-04-26 12:10:34
status_changed: 2024-04-26 12:10:34
type: article
metadata_visibility: show
sword_depositor: 699
creators_name: Ray, JC
creators_name: Darby, D
creators_name: Butzkueven, H
creators_name: Matharu, MS
creators_name: Hutton, EJ
title: Cognitive assessment during the phases of a spontaneous migraine: a prospective cohort study
ispublished: inpress
divisions: UCL
divisions: B02
divisions: C07
divisions: D07
divisions: F82
keywords: Cognition, Cognitive impairment, Headache disorders, Migraine
note: This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.
abstract: INTRODUCTION: 
Cognitive symptoms are reported commonly throughout all phases of a migraine; however, there is a paucity of objective cognitive profiling. Previous studies have been limited by practice effect, and variable populations.

METHODS: 
Participants completed 1 month of daily testing with a computerised cognitive battery involving a simple reaction (SRT), choice reaction (CRT) and a working memory test (WM). Results were correlated with their diary to identify interictal scores, and scores during each phase of a migraine, and non-migraine headache days.


RESULTS: 
A total of 16 patients with episodic migraine participated. During the headache phase of a migraine, responses to SRT, CRT and WM tasks were significantly slower and less accurate than interictally. During the postdrome, WM task performance was slower and less accurate. Non-migraine headache days were not associated with significant change.

CONCLUSION: 
The headache and postdromal phase of a migraine day was associated with objective evidence of cognitive dysfunction in patients with episodic migraine.
date: 2024-04-12
date_type: published
publisher: Springer Science and Business Media LLC
official_url: https://doi.org/10.1007/s10072-024-07520-w
oa_status: green
full_text_type: pub
language: eng
primo: open
primo_central: open_green
verified: verified_manual
elements_id: 2270474
doi: 10.1007/s10072-024-07520-w
medium: Print-Electronic
pii: 10.1007/s10072-024-07520-w
lyricists_name: Matharu, Manjit
lyricists_id: MSMAT80
actors_name: Flynn, Bernadette
actors_id: BFFLY94
actors_role: owner
funding_acknowledgements: [Monash University]
full_text_status: public
publication: Neurological Sciences
event_location: Italy
issn: 1590-1874
citation:        Ray, JC;    Darby, D;    Butzkueven, H;    Matharu, MS;    Hutton, EJ;      (2024)    Cognitive assessment during the phases of a spontaneous migraine: a prospective cohort study.                   Neurological Sciences        10.1007/s10072-024-07520-w <https://doi.org/10.1007/s10072-024-07520-w>.    (In press).    Green open access   
 
document_url: https://discovery.ucl.ac.uk/id/eprint/10191334/1/s10072-024-07520-w.pdf