TY - CHAP M1 - 14539 Y1 - 2024/01/01/ T3 - SEGA ID - discovery10191148 UR - https://doi.org/10.1007/978-3-031-53241-2_6 N2 - Common pixel-based loss functions for image segmentation struggle with the fine-scale structures often found in the aortic vessel tree. In this paper, we propose a Misclassification Loss (MC loss) function, which can effectively suppress false positives and rescue the false negatives. A differentiable eXclusive OR (XOR) operation is implemented to identify these false predictions, which are then minimized through a cross-entropy loss. The proposed MC loss helps the network achieve better performance by focusing on these difficult regions. On the Segmentation of the Aorta SEG.A. 2023 challenge, our method achieves a Dice score of 0.93 and a Hausdorff Distance (HD) of 3.50 mm on a 5-fold split of 56 training subjects. We participated in the SEG.A. 2023 challenge, and the proposed method ranks among the top-six approaches in the validation phase-1. The pre-trained models, source code, and implementation will be made public. SP - 67 ED - Pepe, Antonio ED - Melito, Gian Marco ED - Egger, Jan PB - Springer Nature Switzerland A1 - Khan, Abbas A1 - Asad, Muhammad A1 - Zolotarev, Alexander A1 - Roney, Caroline A1 - Mathur, Anthony A1 - Benning, Martin A1 - Slabaugh, Gregory AV - public TI - Misclassification Loss for Segmentation of the Aortic Vessel Tree CY - Cham, Switzerland T2 - Segmentation of the Aorta. Towards the Automatic Segmentation, Modeling, and Meshing of the Aortic Vessel Tree from Multicenter Acquisition: First Challenge EP - 79 N1 - This version is the author-accepted manuscript. For information on re-use, please refer to the publisher?s terms and conditions. ER -