eprintid: 10188426
rev_number: 9
eprint_status: archive
userid: 699
dir: disk0/10/18/84/26
datestamp: 2024-03-05 09:40:24
lastmod: 2024-10-28 15:28:21
status_changed: 2024-03-05 09:40:24
type: article
metadata_visibility: show
sword_depositor: 699
creators_name: De Angelis, Sara
creators_name: Di Laura, Anna
creators_name: Ramesh, Angelika
creators_name: Henckel, Johann
creators_name: Hart, Alister
title: The role of bone remodeling in measuring migration of custom implants for large acetabular defects
ispublished: inpress
subjects: RNOH
divisions: UCL
divisions: B04
divisions: C05
divisions: F45
keywords: Acetabular defect, biomechanical bone remodeling, custom implants, implant migration,
Paprosky IIIB defect
note: Copyright © 2024 The Authors. Journal of Orthopaedic Research® published by Wiley Periodicals LLC on behalf of Orthopaedic Research Society.
This is an open access article under the terms of the Creative Commons Attribution License, https://creativecommons.org/licenses/by/4.0/, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
abstract: In revision total hip arthroplasty, achieving robust fixation is difficult and implant movement may occur over time. Bone may also rearrange around the implant as a result of mechanical loading, making the measurement of migration challenging. The study aimed to quantify changes in bone shape and implant position 1 year following acetabular reconstruction using custom three-dimensional-printed cups. This observational retrospective cohort study involved 23 patients with Paprosky type IIIB defects. Postop computed tomography scans taken within 1 week of surgery and at 1-year postsurgery were co-registered and analyzed. Three co-registration strategies were implemented including bone-to-bone and implant-to-implant. (1) Co-registration of the ipsilateral innominate bone (diseased anatomy) was used to measure changes in implant position. (2) Co-registration of the implant was carried out to quantify changes in the ipsilateral innominate bone shape. (3) Co-registration of the contralateral innominate bone (nondiseased anatomy) was performed to measure changes in the ipsilateral innominate bone shape and implant position. The median centroid distances (interquartile range [IQR]) were 2.3 mm (IQR: 3.7–1.7 mm) for changes in implant position, 2.4 mm (IQR: 3.6–1.6 mm) for changes in ipsilateral innominate bone shape, and 3.7 mm (IQR: 4.6–3.5 mm) for changes in ipsilateral innominate bone shape and implant position. Following acetabular reconstruction, implant movements and periprosthetic bone remodeling are physiological and of a similar extent. Surgeons and engineers should consider this when performing implant monitoring in these patients.
date: 2024-02-26
date_type: published
publisher: Wiley
official_url: http://dx.doi.org/10.1002/jor.25818
oa_status: green
full_text_type: pub
language: eng
primo: open
primo_central: open_green
verified: verified_manual
elements_id: 2254057
doi: 10.1002/jor.25818
lyricists_name: De Angelis, Sara
lyricists_id: SDEAN50
actors_name: De Angelis, Sara
actors_id: SDEAN50
actors_role: owner
full_text_status: public
publication: Journal of Orthopaedic Research
issn: 0736-0266
citation:        De Angelis, Sara;    Di Laura, Anna;    Ramesh, Angelika;    Henckel, Johann;    Hart, Alister;      (2024)    The role of bone remodeling in measuring migration of custom implants for large acetabular defects.                   Journal of Orthopaedic Research        10.1002/jor.25818 <https://doi.org/10.1002/jor.25818>.    (In press).    Green open access   
 
document_url: https://discovery.ucl.ac.uk/id/eprint/10188426/1/Journal%20Orthopaedic%20Research%20-%202024%20-%20De%20Angelis%20-%20The%20role%20of%20bone%20remodeling%20in%20measuring%20migration%20of%20custom%20implants.pdf