eprintid: 10186762
rev_number: 7
eprint_status: archive
userid: 699
dir: disk0/10/18/67/62
datestamp: 2024-02-08 12:01:33
lastmod: 2024-02-08 12:01:33
status_changed: 2024-02-08 12:01:33
type: article
metadata_visibility: show
sword_depositor: 699
creators_name: Malik, Farihah
creators_name: Crichton, Siobhan
creators_name: Plotnikova, Yulia
creators_name: Latysheva, Inga
creators_name: Samarina, Anna
creators_name: Pokorska-Śpiewak, Maria
creators_name: Gomez, Marisa Navarro
creators_name: Bailey, Heather
creators_name: Thorne, Claire
creators_name: Judd, Ali
creators_name: Turkova, Anna
creators_name: Collins, Intira Jeannie
title: Effectiveness and Safety of Direct-acting Antivirals for Treatment of Adolescents With HCV/HIV Coinfection: Real-world Data From Europe
ispublished: pub
divisions: UCL
divisions: B02
divisions: D65
divisions: D01
divisions: D13
divisions: J38
divisions: G25
keywords: Hepatitis C, HIV, treatment, adolescents, pediatric, directacting antivirals
note: © 2024 The Author(s). Published by Wolters Kluwer Health, Inc.
This is an open-access article distributed under the terms of the Creative
Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBYNC-ND), where it is permissible to download and share the work provided it
is properly cited. The work cannot be changed in any way or used commercially without permission from the journal.
abstract: We evaluated the effectiveness and safety of direct-acting antivirals in adolescents with hepatitis C (HCV)/HIV coinfection using pooled individual patient-level data from 5 European cohorts. Of 122 participants in follow-up from November 2013 to August 2021, 19 were treated <18 years of age; of 15 with HCV RNA available at/after 12 weeks post-treatment, all had sustained virologic response with acceptable safety. This evidence addresses an important gap in knowledge of treatment outcomes in adolescents with HCV/HIV coinfection in real-life settings.
date: 2024-02-02
date_type: published
publisher: Ovid Technologies (Wolters Kluwer Health)
official_url: http://dx.doi.org/10.1097/inf.0000000000004271
oa_status: green
full_text_type: pub
language: eng
primo: open
primo_central: open_green
verified: verified_manual
elements_id: 2228010
doi: 10.1097/INF.0000000000004271
medium: Print-Electronic
pii: 00006454-990000000-00732
lyricists_name: Bailey, Heather
lyricists_name: Thorne, Claire
lyricists_name: Judd, Ali
lyricists_name: Collins, Intira
lyricists_name: Turkova, Anna
lyricists_name: Crichton, Siobhan
lyricists_id: HRBAI10
lyricists_id: CNTHO93
lyricists_id: AJUDD59
lyricists_id: JCOLL88
lyricists_id: ATURK51
lyricists_id: SCRIC86
actors_name: Flynn, Bernadette
actors_id: BFFLY94
actors_role: owner
full_text_status: public
publication: The Pediatric Infectious Disease Journal
event_location: United States
issn: 0891-3668
citation:        Malik, Farihah;    Crichton, Siobhan;    Plotnikova, Yulia;    Latysheva, Inga;    Samarina, Anna;    Pokorska-Śpiewak, Maria;    Gomez, Marisa Navarro;                     ... Collins, Intira Jeannie; + view all <#>        Malik, Farihah;  Crichton, Siobhan;  Plotnikova, Yulia;  Latysheva, Inga;  Samarina, Anna;  Pokorska-Śpiewak, Maria;  Gomez, Marisa Navarro;  Bailey, Heather;  Thorne, Claire;  Judd, Ali;  Turkova, Anna;  Collins, Intira Jeannie;   - view fewer <#>    (2024)    Effectiveness and Safety of Direct-acting Antivirals for Treatment of Adolescents With HCV/HIV Coinfection: Real-world Data From Europe.                   The Pediatric Infectious Disease Journal        10.1097/INF.0000000000004271 <https://doi.org/10.1097/INF.0000000000004271>.       Green open access   
 
document_url: https://discovery.ucl.ac.uk/id/eprint/10186762/1/effectiveness_and_safety_of_direct_acting.732.pdf