eprintid: 10186762 rev_number: 7 eprint_status: archive userid: 699 dir: disk0/10/18/67/62 datestamp: 2024-02-08 12:01:33 lastmod: 2024-02-08 12:01:33 status_changed: 2024-02-08 12:01:33 type: article metadata_visibility: show sword_depositor: 699 creators_name: Malik, Farihah creators_name: Crichton, Siobhan creators_name: Plotnikova, Yulia creators_name: Latysheva, Inga creators_name: Samarina, Anna creators_name: Pokorska-Śpiewak, Maria creators_name: Gomez, Marisa Navarro creators_name: Bailey, Heather creators_name: Thorne, Claire creators_name: Judd, Ali creators_name: Turkova, Anna creators_name: Collins, Intira Jeannie title: Effectiveness and Safety of Direct-acting Antivirals for Treatment of Adolescents With HCV/HIV Coinfection: Real-world Data From Europe ispublished: pub divisions: UCL divisions: B02 divisions: D65 divisions: D01 divisions: D13 divisions: J38 divisions: G25 keywords: Hepatitis C, HIV, treatment, adolescents, pediatric, directacting antivirals note: © 2024 The Author(s). Published by Wolters Kluwer Health, Inc. This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBYNC-ND), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal. abstract: We evaluated the effectiveness and safety of direct-acting antivirals in adolescents with hepatitis C (HCV)/HIV coinfection using pooled individual patient-level data from 5 European cohorts. Of 122 participants in follow-up from November 2013 to August 2021, 19 were treated <18 years of age; of 15 with HCV RNA available at/after 12 weeks post-treatment, all had sustained virologic response with acceptable safety. This evidence addresses an important gap in knowledge of treatment outcomes in adolescents with HCV/HIV coinfection in real-life settings. date: 2024-02-02 date_type: published publisher: Ovid Technologies (Wolters Kluwer Health) official_url: http://dx.doi.org/10.1097/inf.0000000000004271 oa_status: green full_text_type: pub language: eng primo: open primo_central: open_green verified: verified_manual elements_id: 2228010 doi: 10.1097/INF.0000000000004271 medium: Print-Electronic pii: 00006454-990000000-00732 lyricists_name: Bailey, Heather lyricists_name: Thorne, Claire lyricists_name: Judd, Ali lyricists_name: Collins, Intira lyricists_name: Turkova, Anna lyricists_name: Crichton, Siobhan lyricists_id: HRBAI10 lyricists_id: CNTHO93 lyricists_id: AJUDD59 lyricists_id: JCOLL88 lyricists_id: ATURK51 lyricists_id: SCRIC86 actors_name: Flynn, Bernadette actors_id: BFFLY94 actors_role: owner full_text_status: public publication: The Pediatric Infectious Disease Journal event_location: United States issn: 0891-3668 citation: Malik, Farihah; Crichton, Siobhan; Plotnikova, Yulia; Latysheva, Inga; Samarina, Anna; Pokorska-Śpiewak, Maria; Gomez, Marisa Navarro; ... Collins, Intira Jeannie; + view all <#> Malik, Farihah; Crichton, Siobhan; Plotnikova, Yulia; Latysheva, Inga; Samarina, Anna; Pokorska-Śpiewak, Maria; Gomez, Marisa Navarro; Bailey, Heather; Thorne, Claire; Judd, Ali; Turkova, Anna; Collins, Intira Jeannie; - view fewer <#> (2024) Effectiveness and Safety of Direct-acting Antivirals for Treatment of Adolescents With HCV/HIV Coinfection: Real-world Data From Europe. The Pediatric Infectious Disease Journal 10.1097/INF.0000000000004271 <https://doi.org/10.1097/INF.0000000000004271>. Green open access document_url: https://discovery.ucl.ac.uk/id/eprint/10186762/1/effectiveness_and_safety_of_direct_acting.732.pdf