eprintid: 10181850
rev_number: 6
eprint_status: archive
userid: 699
dir: disk0/10/18/18/50
datestamp: 2023-11-23 10:38:58
lastmod: 2023-11-23 10:38:58
status_changed: 2023-11-23 10:38:58
type: article
metadata_visibility: show
sword_depositor: 699
creators_name: Doersam, Annica Franziska
creators_name: Moser, Julia
creators_name: Throm, Jana
creators_name: Weiss, Magdalene
creators_name: Zipfel, Stephan
creators_name: Micali, Nadia
creators_name: Preissl, Hubert
creators_name: Giel, Katrin Elisabeth
title: Maternal eating disorder severity is associated with increased latency of foetal auditory event-related brain responses
ispublished: pub
divisions: UCL
divisions: B02
divisions: D13
divisions: G25
keywords: Social Sciences, Psychology, Clinical, Psychology, anorexia nervosa, brain, development, eating disorders, foetus, fMEG, pregnancy, EVOKED FIELDS, MAGNETOENCEPHALOGRAPHY, CHILDHOOD, ANOREXIA, CHILDREN, NERVOSA, MOTHERS, WOMEN
note: © 2021 The Authors. European Eating Disorders Review published by Eating Disorders Association and John Wiley & Sons Ltd.

This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
abstract: Objective: Maternal eating disorders (EDs) are associated with adverse pregnancy and child outcomes. There is limited research investigating the influence of maternal EDs on foetal brain development. Method: Using foetal magnetoencephalography (fMEG), an auditory sequence was presented for 10 min to assess brain response latencies in foetuses of mothers with (n = 12) and without (n = 11) a history of anorexia nervosa (AN) in the third trimester of pregnancy. ED history and severity were assessed using the structured clinical expert interview eating disorder examination (EDE) and the self-report questionnaire EDE-Q. Results: Foetuses of mothers with AN showed delayed foetal brain responses to auditory stimulation compared to foetuses of control women. Self-reported ED symptom severity explained 34% of variance in foetal brain response latencies in the AN group. Conclusions: ED pathology was strongly associated with foetal brain response latencies in the third trimester with longer latencies in foetuses of women with a history of AN reporting more ED symptoms. Follow-up on the children is pivotal to investigate if fMEG outcomes are associated with later child development.
date: 2022-01
date_type: published
publisher: WILEY
official_url: https://doi.org/10.1002/erv.2870
oa_status: green
full_text_type: pub
language: eng
primo: open
primo_central: open_green
verified: verified_manual
elements_id: 1897874
doi: 10.1002/erv.2870
medium: Print-Electronic
lyricists_name: Micali, Nadia
lyricists_id: NMICA41
actors_name: Flynn, Bernadette
actors_id: BFFLY94
actors_role: owner
funding_acknowledgements: F1292064 [Medical Faculty Tuebingen]; [Stiftung Begabtenforderung Cusanuswerk Open access funding enabled and organized by Projekt DEAL]
full_text_status: public
publication: European Eating Disorders Review
volume: 30
number: 1
pagerange: 75-81
pages: 7
event_location: England
issn: 1072-4133
citation:        Doersam, Annica Franziska;    Moser, Julia;    Throm, Jana;    Weiss, Magdalene;    Zipfel, Stephan;    Micali, Nadia;    Preissl, Hubert;           Doersam, Annica Franziska;  Moser, Julia;  Throm, Jana;  Weiss, Magdalene;  Zipfel, Stephan;  Micali, Nadia;  Preissl, Hubert;  Giel, Katrin Elisabeth;   - view fewer <#>    (2022)    Maternal eating disorder severity is associated with increased latency of foetal auditory event-related brain responses.                   European Eating Disorders Review , 30  (1)   pp. 75-81.    10.1002/erv.2870 <https://doi.org/10.1002/erv.2870>.       Green open access   
 
document_url: https://discovery.ucl.ac.uk/id/eprint/10181850/1/Maternal%20eating%20disorder%20severity.pdf