TY  - JOUR
PB  - WILEY
ID  - discovery10181850
N2  - Objective: Maternal eating disorders (EDs) are associated with adverse pregnancy and child outcomes. There is limited research investigating the influence of maternal EDs on foetal brain development. Method: Using foetal magnetoencephalography (fMEG), an auditory sequence was presented for 10 min to assess brain response latencies in foetuses of mothers with (n = 12) and without (n = 11) a history of anorexia nervosa (AN) in the third trimester of pregnancy. ED history and severity were assessed using the structured clinical expert interview eating disorder examination (EDE) and the self-report questionnaire EDE-Q. Results: Foetuses of mothers with AN showed delayed foetal brain responses to auditory stimulation compared to foetuses of control women. Self-reported ED symptom severity explained 34% of variance in foetal brain response latencies in the AN group. Conclusions: ED pathology was strongly associated with foetal brain response latencies in the third trimester with longer latencies in foetuses of women with a history of AN reporting more ED symptoms. Follow-up on the children is pivotal to investigate if fMEG outcomes are associated with later child development.
KW  - Social Sciences
KW  -  Psychology
KW  -  Clinical
KW  -  Psychology
KW  -  anorexia nervosa
KW  -  brain
KW  -  development
KW  -  eating disorders
KW  -  foetus
KW  -  fMEG
KW  -  pregnancy
KW  -  EVOKED FIELDS
KW  -  MAGNETOENCEPHALOGRAPHY
KW  -  CHILDHOOD
KW  -  ANOREXIA
KW  -  CHILDREN
KW  -  NERVOSA
KW  -  MOTHERS
KW  -  WOMEN
EP  - 81
AV  - public
Y1  - 2022/01//
TI  - Maternal eating disorder severity is associated with increased latency of foetal auditory event-related brain responses
SN  - 1072-4133
UR  - https://doi.org/10.1002/erv.2870
A1  - Doersam, Annica Franziska
A1  - Moser, Julia
A1  - Throm, Jana
A1  - Weiss, Magdalene
A1  - Zipfel, Stephan
A1  - Micali, Nadia
A1  - Preissl, Hubert
A1  - Giel, Katrin Elisabeth
JF  - European Eating Disorders Review
SP  - 75
VL  - 30
N1  - © 2021 The Authors. European Eating Disorders Review published by Eating Disorders Association and John Wiley & Sons Ltd.

This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
IS  - 1
ER  -