eprintid: 10181784 rev_number: 8 eprint_status: archive userid: 699 dir: disk0/10/18/17/84 datestamp: 2023-11-22 13:26:38 lastmod: 2023-11-22 13:26:38 status_changed: 2023-11-22 13:26:38 type: article metadata_visibility: show sword_depositor: 699 creators_name: Giménez, Estela creators_name: Benavente, Elena creators_name: Pascual, Laura creators_name: García-Sampedro, Andres creators_name: López-Fernández, Matilde creators_name: Vázquez, Jose Francisco creators_name: Giraldo, Patricia title: An F2 Barley Population as a Tool for Teaching Mendelian Genetics ispublished: pub divisions: UCL divisions: B02 divisions: C10 divisions: D17 keywords: Genetics education; Mendelian inheritance; qualitative traits; quantitative traits; genetic linkage; molecular markers note: Copyright © 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). abstract: In the context of a general genetics course, mathematical descriptions of Mendelian inheritance and population genetics are sometimes discouraging and students often have serious misconceptions. Innovative strategies in expositive classes can clearly encourage student’s motivation and participation, but laboratories and practical classes are generally the students’ favourite academic activities. The design of lab practices focused on learning abstract concepts such as genetic interaction, genetic linkage, genetic recombination, gene mapping, or molecular markers is a complex task that requires suitable segregant materials. The optimal population for pedagogical purposes is an F2 population, which is extremely useful not only in explaining different key concepts of genetics (as dominance, epistasis, and linkage) but also in introducing additional curricular tools, particularly concerning statistical analysis. Among various model organisms available, barley possesses several unique features for demonstrating genetic principles. Therefore, we generated a barley F2 population from the parental lines of the Oregon Wolfe Barley collection. The objective of this work is to present this F2 population as a model to teach Mendelian genetics in a medium–high-level genetics course. We provide an exhaustive phenotypic and genotypic description of this plant material that, together with a description of the specific methodologies and practical exercises, can be helpful for transferring our fruitful experience to anyone interested in implementing this educational resource in his/her teaching. date: 2021-04 date_type: published publisher: MDPI official_url: https://doi.org/10.3390/plants10040694 oa_status: green full_text_type: pub language: eng primo: open primo_central: open_green verified: verified_manual elements_id: 1873212 doi: 10.3390/plants10040694 medium: Electronic pii: plants10040694 lyricists_name: Garcia Sampedro, Andres lyricists_id: AGARC61 actors_name: Flynn, Bernadette actors_id: BFFLY94 actors_role: owner funding_acknowledgements: [Universidad Politecnica de Madrid] full_text_status: public publication: Plants volume: 10 number: 4 article_number: 694 pages: 13 event_location: Switzerland issn: 2223-7747 citation: Giménez, Estela; Benavente, Elena; Pascual, Laura; García-Sampedro, Andres; López-Fernández, Matilde; Vázquez, Jose Francisco; Giraldo, Patricia; (2021) An F2 Barley Population as a Tool for Teaching Mendelian Genetics. Plants , 10 (4) , Article 694. 10.3390/plants10040694 <https://doi.org/10.3390/plants10040694>. Green open access document_url: https://discovery.ucl.ac.uk/id/eprint/10181784/1/plants-10-00694-v2.pdf