<> <http://www.w3.org/2000/01/rdf-schema#comment> "The repository administrator has not yet configured an RDF license."^^<http://www.w3.org/2001/XMLSchema#string> .
<> <http://xmlns.com/foaf/0.1/primaryTopic> <https://discovery.ucl.ac.uk/id/eprint/10179142> .
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<https://discovery.ucl.ac.uk/id/eprint/10179142> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://purl.org/ontology/bibo/Article> .
<https://discovery.ucl.ac.uk/id/eprint/10179142> <http://purl.org/dc/terms/title> "Oligodendrocyte dynamics dictate cognitive performance outcomes of working memory training in mice"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/eprint/10179142> <http://purl.org/ontology/bibo/abstract> "Previous work has shown that motor skill learning stimulates and requires generation of myelinating oligodendrocytes (OLs) from their precursor cells (OLPs) in the brains of adult mice. In the present study we ask whether OL production is also required for non-motor learning and cognition, using T-maze and radial-arm-maze tasks that tax spatial working memory. We find that maze training stimulates OLP proliferation and OL production in the medial prefrontal cortex (mPFC), anterior corpus callosum (genu), dorsal thalamus and hippocampal formation of adult male mice; myelin sheath formation is also stimulated in the genu. Genetic blockade of OL differentiation and neo-myelination in Myrf conditional-knockout mice strongly impairs training-induced improvements in maze performance. We find a strong positive correlation between the performance of individual wild type mice and the scale of OLP proliferation and OL generation during training, but not with the number or intensity of c-Fos+ neurons in their mPFC, underscoring the important role played by OL lineage cells in cognitive processing."^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/eprint/10179142> <http://purl.org/dc/terms/date> "2023-10-14" .
<https://discovery.ucl.ac.uk/id/document/1662131> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://purl.org/ontology/bibo/Document> .
<https://discovery.ucl.ac.uk/id/eprint/10179142> <http://purl.org/ontology/bibo/volume> "14" .
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<https://discovery.ucl.ac.uk/id/publication/ext-20411723> <http://xmlns.com/foaf/0.1/name> "Nature Communications"^^<http://www.w3.org/2001/XMLSchema#string> .
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<https://discovery.ucl.ac.uk/id/eprint/10179142> <http://purl.org/ontology/bibo/status> <http://purl.org/ontology/bibo/status/published> .
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<https://discovery.ucl.ac.uk/id/eprint/10179142> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10179142#authors> .
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<https://discovery.ucl.ac.uk/id/eprint/10179142> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-508312aa5af23b48708b034e1d486bf6> .
<https://discovery.ucl.ac.uk/id/eprint/10179142> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10179142#authors> .
<https://discovery.ucl.ac.uk/id/eprint/10179142#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_2> <https://discovery.ucl.ac.uk/id/person/ext-508312aa5af23b48708b034e1d486bf6> .
<https://discovery.ucl.ac.uk/id/eprint/10179142> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-d21566a6a9951da2dddd2eaa7cde915e> .
<https://discovery.ucl.ac.uk/id/eprint/10179142> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10179142#authors> .
<https://discovery.ucl.ac.uk/id/eprint/10179142#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_3> <https://discovery.ucl.ac.uk/id/person/ext-d21566a6a9951da2dddd2eaa7cde915e> .
<https://discovery.ucl.ac.uk/id/eprint/10179142> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-18e62b640c4d2d113e3fd45ebd91a1a3> .
<https://discovery.ucl.ac.uk/id/eprint/10179142> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10179142#authors> .
<https://discovery.ucl.ac.uk/id/eprint/10179142#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_4> <https://discovery.ucl.ac.uk/id/person/ext-18e62b640c4d2d113e3fd45ebd91a1a3> .
<https://discovery.ucl.ac.uk/id/eprint/10179142> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-b121dd1d9d8b29a9a3dedfa5f07854e8> .
<https://discovery.ucl.ac.uk/id/eprint/10179142> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10179142#authors> .
<https://discovery.ucl.ac.uk/id/eprint/10179142#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_5> <https://discovery.ucl.ac.uk/id/person/ext-b121dd1d9d8b29a9a3dedfa5f07854e8> .
<https://discovery.ucl.ac.uk/id/eprint/10179142> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-7a6d8a98877df1eb7e22be6a53c08587> .
<https://discovery.ucl.ac.uk/id/eprint/10179142> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10179142#authors> .
<https://discovery.ucl.ac.uk/id/eprint/10179142#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_6> <https://discovery.ucl.ac.uk/id/person/ext-7a6d8a98877df1eb7e22be6a53c08587> .
<https://discovery.ucl.ac.uk/id/eprint/10179142> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-b19b487e98abf64debf496b85738547f> .
<https://discovery.ucl.ac.uk/id/eprint/10179142> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10179142#authors> .
<https://discovery.ucl.ac.uk/id/eprint/10179142#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_7> <https://discovery.ucl.ac.uk/id/person/ext-b19b487e98abf64debf496b85738547f> .
<https://discovery.ucl.ac.uk/id/eprint/10179142> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-6bd73777ab991ebb2047d130c909e8db> .
<https://discovery.ucl.ac.uk/id/eprint/10179142> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10179142#authors> .
<https://discovery.ucl.ac.uk/id/eprint/10179142#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_8> <https://discovery.ucl.ac.uk/id/person/ext-6bd73777ab991ebb2047d130c909e8db> .
<https://discovery.ucl.ac.uk/id/eprint/10179142> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-f283bc653c1992108637973bd2b6f576> .
<https://discovery.ucl.ac.uk/id/eprint/10179142> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10179142#authors> .
<https://discovery.ucl.ac.uk/id/eprint/10179142#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_9> <https://discovery.ucl.ac.uk/id/person/ext-f283bc653c1992108637973bd2b6f576> .
<https://discovery.ucl.ac.uk/id/eprint/10179142> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-ee2524ad5e69b76fd8b334811893f85e> .
<https://discovery.ucl.ac.uk/id/eprint/10179142> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10179142#authors> .
<https://discovery.ucl.ac.uk/id/eprint/10179142#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_10> <https://discovery.ucl.ac.uk/id/person/ext-ee2524ad5e69b76fd8b334811893f85e> .
<https://discovery.ucl.ac.uk/id/eprint/10179142> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-4954168c751ec7a83e13e46c4c153276> .
<https://discovery.ucl.ac.uk/id/eprint/10179142> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10179142#authors> .
<https://discovery.ucl.ac.uk/id/eprint/10179142#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_11> <https://discovery.ucl.ac.uk/id/person/ext-4954168c751ec7a83e13e46c4c153276> .
<https://discovery.ucl.ac.uk/id/eprint/10179142> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-370d2600fa3b468237996ade3f5aa015> .
<https://discovery.ucl.ac.uk/id/eprint/10179142> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10179142#authors> .
<https://discovery.ucl.ac.uk/id/eprint/10179142#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_12> <https://discovery.ucl.ac.uk/id/person/ext-370d2600fa3b468237996ade3f5aa015> .
<https://discovery.ucl.ac.uk/id/eprint/10179142> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-9e0d96a5d2368131e2d5b8f1b11b3c75> .
<https://discovery.ucl.ac.uk/id/eprint/10179142> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10179142#authors> .
<https://discovery.ucl.ac.uk/id/eprint/10179142#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_13> <https://discovery.ucl.ac.uk/id/person/ext-9e0d96a5d2368131e2d5b8f1b11b3c75> .
<https://discovery.ucl.ac.uk/id/person/ext-6bd73777ab991ebb2047d130c909e8db> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery.ucl.ac.uk/id/person/ext-6bd73777ab991ebb2047d130c909e8db> <http://xmlns.com/foaf/0.1/givenName> "David M"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-6bd73777ab991ebb2047d130c909e8db> <http://xmlns.com/foaf/0.1/familyName> "Bannerman"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-6bd73777ab991ebb2047d130c909e8db> <http://xmlns.com/foaf/0.1/name> "David M Bannerman"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-7a6d8a98877df1eb7e22be6a53c08587> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery.ucl.ac.uk/id/person/ext-7a6d8a98877df1eb7e22be6a53c08587> <http://xmlns.com/foaf/0.1/givenName> "Malte"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-7a6d8a98877df1eb7e22be6a53c08587> <http://xmlns.com/foaf/0.1/familyName> "Kaller"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-7a6d8a98877df1eb7e22be6a53c08587> <http://xmlns.com/foaf/0.1/name> "Malte Kaller"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-370d2600fa3b468237996ade3f5aa015> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery.ucl.ac.uk/id/person/ext-370d2600fa3b468237996ade3f5aa015> <http://xmlns.com/foaf/0.1/givenName> "Huiliang"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-370d2600fa3b468237996ade3f5aa015> <http://xmlns.com/foaf/0.1/familyName> "Li"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-370d2600fa3b468237996ade3f5aa015> <http://xmlns.com/foaf/0.1/name> "Huiliang Li"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-ee2524ad5e69b76fd8b334811893f85e> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery.ucl.ac.uk/id/person/ext-ee2524ad5e69b76fd8b334811893f85e> <http://xmlns.com/foaf/0.1/givenName> "Katsutoshi"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-ee2524ad5e69b76fd8b334811893f85e> <http://xmlns.com/foaf/0.1/familyName> "Ogasawara"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-ee2524ad5e69b76fd8b334811893f85e> <http://xmlns.com/foaf/0.1/name> "Katsutoshi Ogasawara"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-b19b487e98abf64debf496b85738547f> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery.ucl.ac.uk/id/person/ext-b19b487e98abf64debf496b85738547f> <http://xmlns.com/foaf/0.1/givenName> "Cassandra"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-b19b487e98abf64debf496b85738547f> <http://xmlns.com/foaf/0.1/familyName> "Sampaio Baptista"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-b19b487e98abf64debf496b85738547f> <http://xmlns.com/foaf/0.1/name> "Cassandra Sampaio Baptista"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-4954168c751ec7a83e13e46c4c153276> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery.ucl.ac.uk/id/person/ext-4954168c751ec7a83e13e46c4c153276> <http://xmlns.com/foaf/0.1/givenName> "Koujiro"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-4954168c751ec7a83e13e46c4c153276> <http://xmlns.com/foaf/0.1/familyName> "Tohyama"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-4954168c751ec7a83e13e46c4c153276> <http://xmlns.com/foaf/0.1/name> "Koujiro Tohyama"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-9e0d96a5d2368131e2d5b8f1b11b3c75> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery.ucl.ac.uk/id/person/ext-9e0d96a5d2368131e2d5b8f1b11b3c75> <http://xmlns.com/foaf/0.1/givenName> "William D"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-9e0d96a5d2368131e2d5b8f1b11b3c75> <http://xmlns.com/foaf/0.1/familyName> "Richardson"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-9e0d96a5d2368131e2d5b8f1b11b3c75> <http://xmlns.com/foaf/0.1/name> "William D Richardson"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-b121dd1d9d8b29a9a3dedfa5f07854e8> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery.ucl.ac.uk/id/person/ext-b121dd1d9d8b29a9a3dedfa5f07854e8> <http://xmlns.com/foaf/0.1/givenName> "Matthew"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-b121dd1d9d8b29a9a3dedfa5f07854e8> <http://xmlns.com/foaf/0.1/familyName> "Grist"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-b121dd1d9d8b29a9a3dedfa5f07854e8> <http://xmlns.com/foaf/0.1/name> "Matthew Grist"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-18e62b640c4d2d113e3fd45ebd91a1a3> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery.ucl.ac.uk/id/person/ext-18e62b640c4d2d113e3fd45ebd91a1a3> <http://xmlns.com/foaf/0.1/givenName> "Yi"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-18e62b640c4d2d113e3fd45ebd91a1a3> <http://xmlns.com/foaf/0.1/familyName> "Jiang"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-18e62b640c4d2d113e3fd45ebd91a1a3> <http://xmlns.com/foaf/0.1/name> "Yi Jiang"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-f283bc653c1992108637973bd2b6f576> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery.ucl.ac.uk/id/person/ext-f283bc653c1992108637973bd2b6f576> <http://xmlns.com/foaf/0.1/givenName> "Heidi"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-f283bc653c1992108637973bd2b6f576> <http://xmlns.com/foaf/0.1/familyName> "Johansen-Berg"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-f283bc653c1992108637973bd2b6f576> <http://xmlns.com/foaf/0.1/name> "Heidi Johansen-Berg"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-508312aa5af23b48708b034e1d486bf6> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery.ucl.ac.uk/id/person/ext-508312aa5af23b48708b034e1d486bf6> <http://xmlns.com/foaf/0.1/givenName> "Stuart G"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-508312aa5af23b48708b034e1d486bf6> <http://xmlns.com/foaf/0.1/familyName> "Nayar"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-508312aa5af23b48708b034e1d486bf6> <http://xmlns.com/foaf/0.1/name> "Stuart G Nayar"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-1eebb55a6cf4c630056ce1d4db9a5630> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery.ucl.ac.uk/id/person/ext-1eebb55a6cf4c630056ce1d4db9a5630> <http://xmlns.com/foaf/0.1/givenName> "Takahiro"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-1eebb55a6cf4c630056ce1d4db9a5630> <http://xmlns.com/foaf/0.1/familyName> "Shimizu"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-1eebb55a6cf4c630056ce1d4db9a5630> <http://xmlns.com/foaf/0.1/name> "Takahiro Shimizu"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-d21566a6a9951da2dddd2eaa7cde915e> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery.ucl.ac.uk/id/person/ext-d21566a6a9951da2dddd2eaa7cde915e> <http://xmlns.com/foaf/0.1/givenName> "Matthew"^^<http://www.w3.org/2001/XMLSchema#string> .
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