TY - INPR ID - discovery10176045 UR - https://doi.org/10.1093/infdis/jiad254 EP - 5 N2 - Many countries affected by the global outbreak of mpox in 2022 have observed a decline in cases. Our mathematical model accounting for heavy-tailed sexual partnership distributions suggests that mpox epidemics can hit the infection-derived herd immunity threshold and begin to decline with less than 1% of sexually active MSM population infected regardless of interventions or behavioural changes. Consistently, we found that many countries and US states experienced an epidemic peak with cumulative cases of around 0.1-0.5% of MSM population. The observed decline in cases may not necessarily be attributable to interventions or behavioural changes primarily. AV - public TI - Accumulation of Immunity in Heavy-Tailed Sexual Contact Networks Shapes Mpox Outbreak Sizes Y1 - 2023/07/04/ SN - 0022-1899 KW - Science & Technology KW - Life Sciences & Biomedicine KW - Immunology KW - Infectious Diseases KW - Microbiology KW - depletion of susceptibles KW - heavy-tailed network KW - herd immunity KW - men who have sex with men KW - mpox PB - OXFORD UNIV PRESS INC JF - The Journal of Infectious Diseases A1 - Murayama, Hiroaki A1 - Pearson, Carl AB A1 - Abbott, Sam A1 - Miura, Fuminari A1 - Jung, Sung-mok A1 - Fearon, Elizabeth A1 - Funk, Sebastian A1 - Endo, Akira N1 - © The Author(s) 2023. Published by Oxford University Press on behalf of Infectious Diseases Society of America. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. ER -